Rubella-Related PH Leads to Infant Mortalities

Pulmonary hypertension can be a devastating disease, especially when it impacts infants and children. A new study in Pediatrics from Nagasaki University and Nagasaki University Hospital in Japan and Khanh Hoa General Hospital and Health Service in Vietnam found high rates of mortality from pulmonary hypertension in…

Macitentan Treatment is Effective for PAH Patients

As new medications for pulmonary hypertension are approved and marketed, it is important to evaluate their efficacy, both absolutely and relative to tried-and-true products. Macitentan, marketed under the name Opsumit by Actelion, is approved to treat pulmonary arterial hypertension patients under the World Health Organization classification of…

PHA Names Stephen L. White As New Chair of Board of Trustees

The Pulmonary Hypertension Association (PHA) recently nominated Stephen L. White as Chair of the Board of Trustees of the organization, after years of his involvement in the PHA’s ongoing national effort to prevent and cure pulmonary hypertension (PH), according to a recent press release. He already serves as chair of…

Inhaled PDGF Inhibitor Prevents PAH Progression in Rats

Inhalation of a small molecule known as PK10453, formally known as (R-phenyl)pyrazin-R-methylnicotinamide, prevented pulmonary arterial hypertension progression in rats who were predisposed for developing pulmonary hypertension. Researchers under the leadership of Dr. Lawrence Zisman at Bassett Medical Center and other institutes in New York and Minnesota published their new…

New PAH-Related Hospitalization Study Released

Any newly-diagnosed pulmonary arterial hypertension (PAH) patient could probably testify to the hardships of having the disease, and new research provides concrete evidence of a substantial burden. More than half of these patients are hospitalized within three years of their diagnosis. Lead author Charles Burger, MD, from the Mayo…

Forced Vital Capacity Found To Be Inadequate When Assessing Scleroderma

Forced vital capacity, or FVC, is defined as the amount of air that can be forcibly exhaled from the lungs after taking the deepest breath possible. Patients suffering from systemic sclerosis, or scleroderma (a chronic systemic autoimmune disease) often undergo this type of spirometry testing to assess their status of…

Systemic Sclerosis Patients At Higher Risk To Develop PAH

A team of over twenty researchers recently found that patients with systemic sclerosis are at high risk to develop pulmonary arterial hypertension (PAH). The study, published in the Seminars in Arthritis & Rheumatism, set out to understand the natural history of pulmonary hypertension (PH) in systemic sclerosis (Ssc),…


A Conversation With Rare Disease Advocates