Actelion recently announced that it has received marketing approval for Opsumit®, the trade name for macitentan, as a treatment for pulmonary arterial hypertension (PAH) from Japan’s Ministry of Health Labor and Welfare. This approval was supported by data collected from a local assessment conducted in Japan and data from the SERAPHIN study, a…

A recent study published in the journal PLoS One found that a single dose of Sildenafil is not associated with clinical improvement of right ventricular (RV) function as measured by cardiovascular magnetic resonance (CMR) in patients with PH-related heart failure (HF). Heart failure…

A new study recently published in The Journal of Heart and Lung Transplantation demonstrated the accuracy and utility of a risk score calculator to predict the one-year survival in patients with pulmonary arterial hypertension. The study is entitled “Prognostic implications of serial risk…

Researchers from the German Center of Lung Research (DZL), Hannover Medical School in Germany recently released findings from a study in which they investigated the theory that the capillary pCO2 (pcCO2) may help in distinguishing between idiopathic pulmonary arterial hypertension (IPAH) and pulmonary hypertension due to heart failure with preserved ejection…

The Pulmonary Hypertension Association (PHA) is organizing another edition of its monthly Patient Telephone Support Group to help people diagnosed with pulmonary hypertension meet other patients and deal with the isolation and burden associated with the disease. This month, the meeting is taking place on March…

A research team from the VU University Medical Center in Amsterdam, the Netherlands recently found that using a combination of assessments for ventricular pressure and pulmonary artery (PA) improves the likelihood of detecting pulmonary hypertension (PH) in patients assessed with computed tomography pulmonary angiography (CTPA). In their study, Onno…

Inhaled Nitric Oxide (iNO) is an FDA approved drug used both in term and near-term neonates suffering from respiratory failure due to pulmonary hypertension. Despite the fact that the drug does not offer clinical benefit in preterm neonates, iNO is still prescribed for these patients, according to a study of researchers…

During the American College of Cardiology (ACC) Congress held this March (14-16) in San Diego, data from the pivotal Selexipag (Uptravi®) Phase III GRIPHON study was shared in an oral presentation. The presentation, entitled “Effect of selexipag on morbidity/mortality in pulmonary arterial hypertension: results of the GRIPHON study” was presented by Dr. Vallerie V.

Findings from a recent study presented this week during the American College of Cardiology/i2 Scientific Session revealed that denervation of the pulmonary artery through catheterization led to a decline in pulmonary arterial hypertension (PAH)-related events and an improvement in heart function and hemodynamic variables in patients with pulmonary hypertension. The…

Researchers at the Cleveland Clinic recently published findings in the journal Circulation revealing that a protein linked to the glucose metabolism pathway can promote cellular proliferation in lung tissues of individuals with idiopathic pulmonary arterial hypertension (IPAH). The study is entitled “O-GlcNAc Transferase…

Results from a recent study published in the Egyptian Journal of Chest Diseases and Tuberculosis suggest that Pulmonary hypertension (PH) in patients with Chronic Obstructive Pulmonary Disease (COPD) is a common co-morbidity along with right sided cardiac changes. Based on the findings, the researchers suggest that…

Biopharmaceutical company Pulmokine has entered into a $1 million investment agreement with Broadview Ventures. The partnership is meant to accelerate the development of the lead drug candidate being developed by Pulmokine, PK10571, for the treatment of pulmonary arterial hypertension (PAH) and enable the initiation of its phase 1 clinical trial. The CEO…