Pathophysiology of Pulmonary Arterial Hypertension


An educational overview of three principal pathways—endothelin, nitric oxide, and prostacyclin—involved in the pathogenesis of pulmonary arterial hypertension (PAH).

This site is intended for U.S. healthcare professionals only. It features information about pulmonary arterial hypertension (PAH). PAH is defined hemodynamically as a mean pulmonary arterial pressure greater than or equal to 25 millimeters of mercury, with a pulmonary capillary wedge pressure of less than or equal to 15 millimeters of mercury.

Learn more about pulmonary arterial hypertension:

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