News

Actelion Launches Opsumit For Pulmonary Arterial Hypertension in England

Swiss biotech company Actelion Pharmaceuticals has launched Opsumit (macitentan) as a new treatment option for patients with pulmonary arterial hypertension (PAH) in England, where approximately 3,000 people receive disease-targeted drug therapy for the condition. This comes as significant news for Actelion, after the Institut National d’Excellence en Santé…

Obesity Paradox Uncovered In Pulmonary Hypertension

Jose Caceres, MD, from Jacobi Medical Center/Albert Einstein College of Medicine, recently presented research at the 2014 American Thoracic Society International Conference that adds fuel to the “obesity paradox phenomenon.” Whereas obesity (higher body mass index, or BMI) is usually associated with poorer health outcomes, Dr. Caceres’…

Limited Exercise Capacity In PAH Explored By Researchers In Recent Study

It is commonly known that exercise capacity is impaired in pulmonary arterial hypertension (PAH).  Thanks to a recent study, researchers were able to test a hypothesis on why this is the case, with the idea that perhaps cardiovascular reserve anomalies are in fact linked with an impaired hemodynamics response…

FDA Postmarket Trial for PAH Treatment Bosentan Reveals Drug Does Not Reduce Time To Mortality Rates

Drug maker Actelion has indicated that the company’s Food and Drug Administration (FDA)–approved pulmonary arterial hypertension (PAH) drug Bosentan, which is also known under the brand names of Actelion and Tracleer, recently failed a key FDA postmarket test. The test, which was part of the postmarket COMPASS 2 trial, revealed that Bosentan did not reduce time…

Early-Stage Pulmonary Arterial Hypertension Therapy From Pulmokine Awarded $1.5 Million Through Federally Funded VITA Contract

Rensselaer, New York-based biopharmaceutical company Pulmokine recently made a major announcement regarding the company’s efforts in developing a novel therapy for pulmonary arterial hypertension (PAH). In a press release from late March, Pulmokine indicated that that the National Heart, Lung, and Blood Institute (NHLBI), a division of the federally run National…