PAH News

June 1, 2020June 1, 2020

Pulmonary Artery Denervation Helps to Treat PAH, Trial Suggests

News, PAH News

Pulmonary artery denervation was found to be safe and to improve the health of people with pulmonary arterial hypertension (PAH), according to results of an early clinical trial. The study, ... Read more

May 29, 2020May 29, 2020

Epigenetic Changes May Boost PAH Development, Study Reports

News, PAH News

Changes in the epigenetic profile — a collection of marks that turn genes on and off — of pulmonary arterial endothelial cells from people with pulmonary arterial hypertension (PAH) ... Read more

May 27, 2020May 27, 2020

Kalytera to Acquire R-107, Potential Liquid Nitric Oxide Treatment for PAH

News, PAH News

Kalytera Therapeutics intends to acquire Salzman Group, a company developing R-107 — a liquid form of nitric oxide — to possibly treat pulmonary arterial hypertension (PAH), lung disease associated with COVID-19, and other ... Read more

May 20, 2020May 20, 2020

Study Reveals How Sotatercept Works in PAH Rat Model, Supporting Its Potential for Patients

News, PAH News

Newly published research has detailed the underlying biochemical process behind Acceleron Pharma’s investigational therapy sotatercept (ACE-011) for the potential treatment of people with pulmonary arterial hypertension (PAH). The findings, ... Read more

May 11, 2020May 11, 2020

At-home System of Inhaled Nitric Oxide Treats PAH Patient Infected With COVID-19

News, PAH News

At-home treatment with inhaled nitric oxide through Genosyl, a tankless delivery system, was used successfully to manage pulmonary arterial hypertension (PAH) complicated by COVID-19 in a patient, according to a ... Read more

May 8, 2020May 8, 2020

EMA Grants Priority Medicines Designation to Sotatercept for PAH

News, PAH News

The European Medicines Agency (EMA) has granted priority medicines (PRIME) designation to investigational therapy sotatercept (ACE-011) for the treatment of patients with pulmonary arterial hypertension (PAH). This designation is ... Read more

May 4, 2020May 4, 2020

PAH Trials Pausing Enrollment for COVID-19, United Therapeutic Says

News, PAH News, PH News

United Therapeutics has temporarily stopped enrolling patients in ongoing clinical trials of treprostinil-based therapies for pulmonary arterial hypertension (PAH) amid the COVID-19 pandemic, the company announced. Treprostinil is a man-made version of the ... Read more

April 27, 2020April 27, 2020

Benefits of Orenitram for PAH Patients Detailed in New Data

News, PAH News

United Therapeutics’ Orenitram (treprostinil) improves heart function and lowers risk status in people with pulmonary arterial hypertension (PAH) who had begun treatment with another approved therapy, new data from a Phase ... Read more

April 23, 2020April 24, 2020

FDA Grants Orphan Drug Designation to Cereno Scientific’s Lead Candidate CS1 for PAH

News, PAH News

The U.S. Food and Drug Administration (FDA) has granted orphan drug designation to CS1, Cereno Scientific’s lead therapy candidate for the treatment of pulmonary arterial hypertension (PAH). CS1 is ... Read more

April 22, 2020April 22, 2020

Novel IPAH Mutations Found in Chinese Patients, Study Reports

News, PAH News

Newly identified mutations that contribute to a higher susceptibility of idiopathic pulmonary arterial hypertension (IPAH) in people from China, were found in a pathway commonly targeted by therapies that ... Read more

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