PAH News

May 23, 2018May 23, 2018

Acceleron Launches PULSAR Phase 2 Trial Testing Potential PAH Therapy Sotatercept

News, PAH News

Acceleron Pharma, a biopharmaceutical company focused on rare diseases, has announced the start of the PULSAR Phase 2 clinical trial assessing the safety and effectiveness of sotatercept (ACE-011) in adults with pulmonary ... Read more

May 16, 2018May 16, 2018

Scottish Agency Recommends Uptravi for PAH Treatment Through National Health System

News, PAH News, PH News

Scottish patients with pulmonary arterial hypertension (PAH) can now be treated with Actelion‘s Uptravi (selexipag) through the country’s National Health System (NHS) after a positive recommendation from the Scottish Medicines ... Read more

May 14, 2018May 14, 2018

Reata Recruiting More CTD-PAH Patients for Phase 3 CATALYST Trial Testing Bardoxolone Methyl

News, PAH News, PH News

Reata Pharmaceuticals is currently recruiting participants for its Phase 3 CATALYST trial assessing the effectiveness of bardoxolone methyl in connective tissue disease-associated pulmonary arterial hypertension (CTD-PAH). After analysis of ... Read more

May 9, 2018May 9, 2018

Age, Certain Comorbidities Predict Outcomes in Idiopathic PAH Patients, Study Shows

News, PAH News

Age, ischemic heart disease, and kidney dysfunction are important predictors of outcomes in patients with idiopathic pulmonary arterial hypertension (IPAH), a Swedish study shows. The research, “Impact of age and ... Read more

May 4, 2018May 4, 2018

Six-minute Walk Test Still Key in Predicting Long-Term PAH Outcomes, Study Confirms

News, PAH News

Patients with pulmonary arterial hypertension (PAH) who can walk more than 400 meters (437 yards) on a six-minute walk test have better long-term prognosis, with lower risk of PAH-related ... Read more

April 26, 2018April 26, 2018

Right Ventricular Function Determines Survival in PAH Patients, Study Reports

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Right ventricular function of the heart is the primary determining factor of survival in patients with pulmonary arterial hypertension (PAH) receiving specific treatments, a study suggests. The study, “Predictors ... Read more

April 23, 2018April 23, 2018

Supplemental Oxygen Use Has Positive Effects in PAH Patients, Study Shows

News, PAH News

Supplemental oxygen use is associated with improved survival in a subpopulation of patients with pulmonary arterial hypertension (PAH), a study has found. Current guidelines that recommend oxygen supplementation therapy ... Read more

April 17, 2018April 17, 2018

Researchers Identify Rare Mutations That Could Lead to Pulmonary Hypertension

News, PAH News

British researchers have identified rare mutations of four genes that could lead to pulmonary arterial hypertension. The team said scientists might be able to develop PAH treatments around the ... Read more

April 16, 2018April 16, 2018

Protein That Regulates Calcium Could Become Target for PAH Therapy, Study Reports

News, PAH News

University of Edinburgh researchers identifying a protein that could become a target for treating pulmonary arterial hypertension, or PAH. They discovered that the two-pore segment channel 2 protein, or TPC2, in ... Read more

April 13, 2018April 13, 2018

Ralinepag Reduces PAH Patients’ Risk of Death, Phase 2 Trial Shows

News, PAH News

Arena Pharmaceuticals’ ralinepag reduced the risk of pulmonary arterial hypertension patients dying, a Phase 2 clinical trial showed. Temple University Professor Raymond Benza will present the results at the International Society for ... Read more

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