PAH News

September 9, 2019September 11, 2019

Two Non-Invasive Tests Predict PAH Prognosis in Patients with Congenital Heart Disease, Study Reveals

News, PAH News

Only two non-invasive diagnostic tests are required to best predict the risk of adverse events in people with congenital heart disease (CHD)-associated pulmonary arterial hypertension (PAH), a new study ... Read more

September 6, 2019September 6, 2019

Swedish Men and Women with IPAH Have Similar Survival Rates, Study Says

News, PAH News

Swedish men and women who have been diagnosed with idiopathic pulmonary arterial hypertension (IPAH) in recent years have similar survival rates, study says. The study, “Sex-specific differences and survival in ... Read more

September 5, 2019September 5, 2019

Blocking Inflammatory Signaling in Specific Pulmonary Artery Cells Might Treat PAH, Study Says

News, PAH News

Targeting the pro-inflammatory TGF-β signaling pathway in specific cells of the pulmonary arteries — those with high levels of a protein called periostin — shows promise in treating pulmonary ... Read more

August 30, 2019September 3, 2019

Common Lung Infections May Trigger PAH in People with At-risk Mutations, Rat Study Finds

News, PAH News

Lung inflammation caused by a seemingly treatable and common infection may drive the onset of pulmonary arterial hypertension (PAH) in people who carry genetic risk factors for the disease. ... Read more

August 29, 2019August 29, 2019

PDE5i-ERA Combo Improves Exercise Capacity, Reduces Risk of Death in PAH, Review Says

News, PAH News

A combination therapy of endothelin receptor antagonists (ERA) plus phosphodiesterase-5 inhibitors (PDE5i) — two different agents that induce blood vessels’ widening and relaxation —improves exercise capacity, and reduces the ... Read more

August 22, 2019August 27, 2019

People Born Prematurely More Likely to Develop PAH Later in Life, Study Says

News, PAH News

People who were born prematurely, especially in recent years, are more likely to develop pulmonary arterial hypertension (PAH) later in life, a study says. The findings of the study, ... Read more

August 21, 2019August 28, 2019

Uric Acid May Be Predictive Biomarker of PAH in Scleroderma Patients, Study Shows

News, PAH News

Blood levels of uric acid may be a predictive biomarker of pulmonary arterial hypertension (PAH) in people with scleroderma, according to a recent study. The levels of this normal ... Read more

August 7, 2019August 7, 2019

Phase 2a Trial of Rodatristat Ethyl, Potential Oral PAH Therapy, Begins Dosing

News, PAH News

A Phase 2a trial testing the potential oral treatment rodatristat ethyl in patients with pulmonary arterial hypertension (PAH) has begun dosing, its developer announced. Rodatristat ethyl (or RVT-1201), the ... Read more

July 31, 2019August 5, 2019

Better Risk Assessment Needed to Improve Care in PAH, International Survey Shows

News, PAH News

While physicians worldwide are conducting multi-parametric risk assessments to evaluate pulmonary arterial hypertension (PAH), they are not doing so to the extent recommended by current guidelines, results from an ... Read more

July 29, 2019July 29, 2019

Nintedanib Lowers Lung Blood Pressure in Rat Model of PAH, Study Shows

News, PAH News

Treatment with nintedanib lowered lung blood pressure in a rat model of pulmonary arterial hypertension by preventing cells of blood vessel walls from changing identity, and by inhibiting smooth ... Read more

Pin It on Pinterest