PAH News

December 5, 2018December 6, 2018

Uptravi, PAH Treatment, Now Publicly Funded in 9 of 10 Canadian Provinces

News, PAH News

Uptravi (selexipag) is now available with public funding for pulmonary arterial hypertension (PAH) patients in Canada living in nine of the country’s 1o provinces, patient groups announced. The governments ... Read more

December 3, 2018December 4, 2018

Morphogen-IX Announces MGX292 as Treatment Candidate for PAH

News, PAH News

Biotechnology company Morphogen-IX recently announced that it will be further developing MGX292 as its treatment candidate for pulmonary arterial hypertension (PAH). The company’s decision is supported by previous preclinical studies ... Read more

November 30, 2018December 4, 2018

PhaseBio Advances New Phase 2b Trial to Test PB1046 in Patients with PAH

News, PAH News

PhaseBio Pharmaceuticals started dosing its investigational compound PB1046 in patients with pulmonary arterial hypertension (PAH) in a Phase 2b clinical trial. The first patient to receive the therapy was ... Read more

November 29, 2018December 5, 2018

Specific Bone Marrow Cells Drive PAH Development, Blocking Serotonin Receptors a Potential Treatment, Study Suggests

News, PAH News, PH News

A subset of bone marrow cells known as proangiogenic cells (PACs) may drive the development of pulmonary arterial hypertension (PAH), according to a study that also showed that blocking ... Read more

November 21, 2018November 28, 2018

Arena Pharmaceuticals, United Therapeutics Reach Global Licensing Agreement for Ralinepag

News, PAH News

Arena Pharmaceuticals and United Therapeutics have reached a global licensing agreement for the pulmonary arterial hypertension (PAH) therapy candidate ralinepag. Ralinepag (APD811) is a next-generation, selective prostacyclin receptor agonist designed for oral ... Read more

November 16, 2018November 26, 2018

Heart’s Right Side Size Affects Heart Function in PAH Patients, Study Shows

News, PAH News

Pulmonary arterial hypertension (PAH) patients with an enlarged right side of the heart show higher pulmonary arterial pressures and increased resistance to blood flow compared to healthy controls, a ... Read more

November 15, 2018November 26, 2018

Revatio at Low Doses Safe and of Benefit to Children with PH, Study Reports

News, PAH News, PH News

Revatio (sildenafil) in low doses is safe and can be of benefit to children with pulmonary hypertension (PH), particularly those with early lung disease, a study reports. With this work, the ... Read more

November 14, 2018November 28, 2018

Range of Clinical Trials Testing INOpulse System for PAH, PH-linked Lung Diseases, Bellerophon Announces

News, PAH News, PH News

INOpulse is advancing in a number of clinical trials as a potential treatment of pulmonary hypertension (PH) associated with several lung diseases, Bellerophon Therapeutics reported in a recent announcement. ... Read more

November 8, 2018November 14, 2018

Transgelin Protein May Provide Clues on PAH Progression in Congenital Heart Disease, Study Says

News, PAH News

Transgelin, a smooth muscle protein, is abundant in patients with irreversible pulmonary arterial hypertension (PAH) secondary to congenital heart disease and may contribute to PAH progression, a study reports. The study, ... Read more

November 2, 2018November 9, 2018

Liquidia Completes Enrollment for Safety Portion of Phase 3 Trial on LIQ861 for PAH

News, PAH News

Liquidia Technologies has completed the enrollment for the safety part of a Phase 3 trial evaluating the safety and tolerability of LIQ861, an inhaled dry power formulation of treprostinil for the ... Read more

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