PAH News

July 17, 2020July 17, 2020

Interleukin-32 Shows Potential as Early Biomarker for PAH in Scleroderma Patients

News, PAH News

A protein called interleukin-32 may serve as a biomarker for pulmonary arterial hypertension (PAH) in scleroderma patients, for whom PAH is a severe complication. The study reporting the findings, “Interleukin-32 ... Read more

July 15, 2020July 15, 2020

Liquidia to Expand PAH Treatment Efforts With RareGen Acquisition

News, PAH News

Liquidia Technologies, a company developing an inhaled form of treprostinil for pulmonary arterial hypertension (PAH), has established an agreement to acquire the rare disease company and marketer of generic treprostinil ... Read more

June 29, 2020July 17, 2020

Sotatercept Reduces Heart Strain, Improves Functional Capacity in PAH, Data Show

News, PAH News

Sotatercept (ACE-011) leads to clinically meaningful reductions in heart strain and improvements in functional capacity in patients with pulmonary arterial hypertension (PAH), top-line data from a Phase 2 trial ... Read more

June 22, 2020June 22, 2020

Tiny RNA Molecule, MicroRNA-483, May Help Ease PAH, Early Study Finds

News, PAH News

Increasing the levels of a tiny RNA molecule known as microRNA-483 enhanced the function of endothelial cells and eased the symptoms of pulmonary arterial hypertension (PAH) in rat models of the disease, a ... Read more

June 19, 2020June 19, 2020

Computer Model Seen to Accurately Distinguish PAH From PVOD

News, PAH News

Gene expression patterns in the lungs can help distinguish pulmonary arterial hypertension (PAH) from pulmonary veno-occlusive disease (PVOD) — a subtype in which the narrowing of veins, instead of ... Read more

June 17, 2020June 17, 2020

R-107 Shows Promise in Early Study for PAH Linked to COVID-19

News, PAH News

Kalytera Therapeutics has announced positive early results for R-107, a liquid form of nitric oxide designed to treat pulmonary arterial hypertension (PAH) associated with COVID-19. Nitric oxide, known as ... Read more

June 15, 2020August 12, 2020

Aerami, Vectura Sign Deal to Develop Nebulized Imatinib

News, PAH News

Aerami Therapeutics has entered an agreement with Vectura Group to develop and commercialize an inhaled form of imatinib — an approved cancer therapy — for the treatment of people ... Read more

June 5, 2020September 8, 2020

Bayer Offering Grants Up to $1M to Advance PAH, CTEPH Research and Care

CTEPH News, News, PAH News, PH News

Bayer has opened its second annual Pulmonary Hypertension Accelerated Bayer (PHAB) Awards, a grant funding program to support clinical research projects into pulmonary hypertension (PH), particularly those focused on pulmonary ... Read more

June 1, 2020June 1, 2020

Pulmonary Artery Denervation Helps to Treat PAH, Trial Suggests

News, PAH News

Pulmonary artery denervation was found to be safe and to improve the health of people with pulmonary arterial hypertension (PAH), according to results of an early clinical trial. The study, ... Read more

May 29, 2020May 29, 2020

Epigenetic Changes May Boost PAH Development, Study Reports

News, PAH News

Changes in the epigenetic profile — a collection of marks that turn genes on and off — of pulmonary arterial endothelial cells from people with pulmonary arterial hypertension (PAH) ... Read more

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