PAH News

July 29, 2019July 29, 2019

Nintedanib Lowers Lung Blood Pressure in Rat Model of PAH, Study Shows

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Treatment with nintedanib lowered lung blood pressure in a rat model of pulmonary arterial hypertension by preventing cells of blood vessel walls from changing identity, and by inhibiting smooth ... Read more

July 26, 2019July 26, 2019

Specific Heart Rhythm Parameters Help Predict PH, Study Suggests

The heart rhythm of patients with pulmonary hypertension (PH) has limited ability to adjust to changes, compared to unaffected people used as controls in a new pilot study. The ... Read more

July 24, 2019July 24, 2019

Anti-inflammatory Diet Reduces Heart, Skeletal Muscle Changes in PAH Mice

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An anti-inflammatory diet with high amounts of protein, fish oil, the amino acid leucine, and oligosaccharides reduced changes in heart and skeletal muscle in a female mice model of ... Read more

July 18, 2019July 18, 2019

Long-term Orenitram Use Can Help PAH Patients Walk Longer Distances, Extension Trial Finds

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Long-term use of Orenitram led to moderate but durable, and dose dependent, improvements in exercise capacity in pulmonary arterial hypertension (PAH) patients, results from an open-label extension trial show. These findings ... Read more

July 17, 2019July 17, 2019

Raising Levels of Nur77 May Help Halt Progression of PH, Study Suggests

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Increasing levels of the receptor Nur77 in cells lining the blood vessels of patients with pulmonary hypertension (PH) may help halt progression of the disease by enhancing the signaling ... Read more

July 15, 2019July 15, 2019

Left Heart Dysfunction Plays Key Role in Severe PAH, Study Suggests

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Left heart dysfunction may play an important role in severe pulmonary arterial hypertension (PAH), and should be monitored to optimize treatment, according to new research. The study, “Impact of ... Read more

July 12, 2019July 12, 2019

Extracorporeal Life Support Helps iPAH Patients Needing Lung Transplant, but Outcomes Remain Poor

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Extracorporeal life support improves the lung performance of people with idiopathic pulmonary arterial hypertension (iPAH) who need a lung transplant. But patients usually enter the transplant list at advanced stages ... Read more

July 11, 2019July 11, 2019

Implantable CardioMEMS System Useful in Predicting Heart Failure Risk in PAH, Study Shows

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Abbott’s CardioMEMS HF system — a wireless heart failure monitor — can be safely used to monitor blood flow (hemodynamics) changes and help predict the risk of heart failure ... Read more

July 3, 2019July 3, 2019

Revatio Infusions Add No Benefit to Inhaled NO for Newborns With PPHN, Trial Shows

News, PAH News, PH News

Into the vein (intravenous) injections of Revatio (sildenafil) have no added benefit over inhaled nitric oxide (iNO) used alone in treating newborns with persistent pulmonary hypertension (PPHN), a Phase ... Read more

July 1, 2019July 1, 2019

Goal-oriented Sequential Combo Therapy Benefits PAH Patients, Study Says

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Use of sequential combination therapy focused on changes in exercise capacity improves health-related quality of life (HRQoL) in patients with newly diagnosed pulmonary arterial hypertension (PAH), according to a ... Read more

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