PH News

April 17, 2020April 17, 2020

Exosomes from Stem Cells May Slow Vascular Remodeling in PAH

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Small vesicles, called exosomes, released by mesenchymal stem cells helped to ease vascular remodeling in a rat model of pulmonary hypertension (PH), a study reports. The study “Mesenchymal stromal ... Read more

April 10, 2020April 10, 2020

HELP Trial Testing Levosimendan Infusion in PH-HFpEF Patients Completed

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Tenax Therapeutics has completed its Phase 2 HELP clinical trial testing levosimendan as a potential treatment for patients with pulmonary hypertension and heart failure with preserved ejection fraction (PH-HFpEF). Top-line trial ... Read more

April 3, 2020April 3, 2020

Experts Issue Guidance on Use of Oral PPAs, Like Uptravi, in Treating PAH

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A consensus on the use of oral prostacyclin pathway agents (PPAs), like Uptravi (selexipag), as an add-on to standard therapies for certain types of pulmonary arterial hypertension (PAH) was ... Read more

March 27, 2020March 27, 2020

PHA Adds Four Newly Accredited Centers of Comprehensive Care to its Network

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After demonstrating an ability to deliver top-shelf care to patients with pulmonary hypertension (PH), four sites have been added to the Pulmonary Hypertension Association’s (PHA) network of Centers of Comprehensive ... Read more

March 25, 2020March 25, 2020

COVID-19 Patient with PH Treated with iNO Via Genosyl, VERO Biotech Announces

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The first person with coronavirus disease 2019 (COVID-19) complicating pulmonary hypertension (PH) has received at-home treatment with inhaled nitric oxide (iNO), delivered through the Genosyl system, according to VERO Biotech, manufacturer ... Read more

March 13, 2020March 13, 2020

Bellerophon, FDA Agree on Design of Phase 3 INOPulse Clinical Trial

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Bellerophon Therapeutics has reached an agreement with the U.S. Food and Drug Administration (FDA) setting the design of an upcoming, pivotal Phase 3 clinical trial testing INOpulse, an investigational ... Read more

March 9, 2020March 9, 2020

Persistent PH in Newborns Linked to 3 Rare Genetic Mutations, Study Finds

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Genetic screening of patients with persistent pulmonary hypertension of the newborn (PPHN) found three rare mutations associated with the condition, suggesting it has a genetic basis, a study reports. ... Read more

February 26, 2020February 26, 2020

Young PH Researchers Boosted by Foundation Partner Grants

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The ATS Foundation Research Program and Pulmonary Hypertension Association have announced the 2019 recipients of their partner grants, totaling $210,000, for young researchers dedicated to scientific discovery and better patient ... Read more

February 24, 2020February 24, 2020

Using INOpulse Nitric Oxide Device Improves Blood Flow in Lungs in PH-PF, New Trial Data Suggest

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Use of Bellerophon Therapeutics’ INOpulse device — which provides nitric oxide to the lungs — significantly improved parameters related to blood flow in the lungs in people with pulmonary ... Read more

February 12, 2020February 12, 2020

Aria CV’s PH System Designated as Breakthrough Device by FDA

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Aria CV‘s medical device for treating pulmonary hypertension (PH) has been given a Breakthrough Device designation by the United States Food and Drug Administration (FDA). The Aria CV PH ... Read more

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