Combination therapy — a treatment approach used to target multiple pathways involved in pulmonary arterial hypertension (PAH) — improves…
Articles by Vanda Pinto, PhD
Levels of the Wnt inhibitory factor 1 (WIF-1) protein were elevated in the blood of people with pulmonary hypertension…
A research form of Keros Therapeutics’ investigational therapy KER-012, called RKER-012, reduced lung inflammation and scarring (fibrosis) in a…
A mean pulmonary artery pressure (mPAP) — blood pressure in the lungs — of less than 40 mmHg (millimeters of…
Depression and anxiety are common in people with pulmonary hypertension (PH), especially for those living in Asia, a review…
Identification of mutations in the ATP13A3 gene, which are associated with a severe form of pulmonary arterial hypertension (PAH),…
The levels of Piezo1, an ion channel that senses membrane tension in cells, was found to be increased in the…
Infusion with Ferinject (ferric carboxymaltose) safely treated people with pulmonary arterial hypertension (PAH) and iron deficiency, easing disease symptoms,…
Breathing oxygen-enriched air can significantly improve exercise performance in people with pulmonary hypertension (PH) linked to heart failure with…
Higher levels of chloride in pulmonary artery smooth muscle cells (PASMCs) may contribute to the development of pulmonary hypertension…
Note: This story was updated Aug. 11, 2021, to clarify that the researchers are not affiliated with the Virginia Tech…
A protein known as cell division cycle protein 2 (CDC2) enhances the proliferation of pulmonary artery smooth muscle cells —…