News

Inhaled imatinib treatment found safe in healthy people in study

Treatment with AER-901, an inhaled formulation of imatinib that Aerami Therapeutics is developing as a treatment for two forms of pulmonary hypertension, was generally well-tolerated in a Phase 1 study conducted with healthy volunteers. That’s according to safety data presented by Aerami at the 2023 American Thoracic Society…

KER-012 reduces markers of heart damage, fibrosis in Phase 1 study

Treatment with KER-012, an experimental therapy Keros Therapeutics is developing to treat pulmonary arterial hypertension (PAH), lowered markers of heart damage, fibrosis, and inflammation in a Phase 1 clinical trial that tested the therapy in healthy postmenopausal women. Keros presented the findings at the American Thoracic Society (ATS)…

Team PHenomenal Hope to host first symposium on PH research

Team PHenomenal Hope will host its inaugural symposium — PHenomenal Hope 2023: Knowledge, Research & Advocacy in PH — on Dec. 15 in Boston, allowing renowned experts, young researchers, and healthcare providers to share efforts on pulmonary hypertension (PH) clinical research and care. “Team PHenomenal Hope has grown…

Importance of clinical worsening criteria vary, survey finds

People with pulmonary arterial hypertension (PAH) and their caregivers place different value on the parameters used to evaluate clinical worsening in trials, according to the findings of a survey in Canada. Patients attributed significant importance to lacking clinical improvement, needing long-term oxygen therapy, and any decrease in health-related quality…

Benefits seen with levosimendan in preterm infants with PH: Study

Treatment with levosimendan — a medication seen to improve cardiac function — was associated with rapid clinical benefits in preterm infants with heart problems and pulmonary hypertension (PH), a study in Germany reports. The response to treatment was independent of the babies’ birth weight and how far along…

A Conversation With Rare Disease Advocates