News

Morphogen-IX Announces MGX292 as Treatment Candidate for PAH

Biotechnology company Morphogen-IX recently announced that it will be further developing MGX292 as its treatment candidate for pulmonary arterial hypertension (PAH). The company’s decision is supported by previous preclinical studies that have shown the potential of MGX292, a signaling protein analogue, as a safe and effective therapy for PAH.

Arena Pharmaceuticals, United Therapeutics Reach Global Licensing Agreement for Ralinepag

Arena Pharmaceuticals and United Therapeutics have reached a global licensing agreement for the pulmonary arterial hypertension (PAH) therapy candidate ralinepag. Ralinepag (APD811) is a next-generation, selective prostacyclin receptor agonist designed for oral delivery. Prostacyclin, produced by cells lining the walls of blood vessels, is a vasodilator (a widener of blood…

Transgelin Protein May Provide Clues on PAH Progression in Congenital Heart Disease, Study Says

Transgelin, a smooth muscle protein, is abundant in patients with irreversible pulmonary arterial hypertension (PAH) secondary to congenital heart disease and may contribute to PAH progression, a study reports. The study, “Transgelin as a potential target in the reversibility of pulmonary arterial hypertension secondary to congenital heart disease,” was…