Pulmonary Hypertension News Forums Forums PH Care and Treatment Treatments and Therapies Sorafenib Shown to Reverse PAH in Rat Model

  • Kathleen Sheffer

    Member
    August 13, 2018 at 1:27 pm

    This is so cool! The results suggested that sorafenib “significantly and dose-dependently reversed cardiopulmonary remodeling and PAH at even a low dose (10  mg/kg).” The researchers believe “a low-dose sorafenib therapy may be a suitable therapeutic agent for PAH.” This is exciting, especially because this medication is already used in humans to treat cancer. I hope the trial advances quickly.

    Developments like this give me hope that a cure for PH is on its way. What kind of research developments do you look for?

    There are lots of trials done on medications already being used to treat PH, but I’m most excited about new medications or new pathways to target. What gets you excited?

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