In pulmonary arterial hypertension (PAH), blood vessel cells in the lungs release exosomes, or cellular shipping containers, filled with a signaling molecule called microRNA-21 (miR-21) that are taken up by heart cells to help limit heart damage, a new study shows. “These findings identify exosomal miR-21 as a key…
Treatment with molecular shipping containers called extracellular vesicles, loaded with a signaling molecule called cAMP, reduced the severity of pulmonary hypertension (PH) in a rat model of the disease, a new study reports. The data indicated that these packages of signaling molecules, which they dubbed cAMP-EVs, reduced the abnormal…
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Sometimes a news headline rattles you so deeply that you’re still thinking about it nearly two months later. I probably can’t shake this particular headline because I was at the airport when I read the article. Let’s rewind to the week before last Christmas, when I was preparing to fly…
The one-minute sit-to-stand test (STST), which measures the number of times a patient can sit down and stand up from a chair in 1 min, may predict adverse outcomes in adults with pulmonary hypertension (PH), according to a study. In particular, worse performance in the STST (14 repetitions or…
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