2. Endothelin receptor antagonists
Endothelin is the substance that causes the blood vessels to narrow. Endothelin receptor antagonists are medications that reverse this effect. Bosentan (Tracleer) is one of these medications; whilst taking it, pulmonary hypertension patients may see their energy levels improved and their symptoms relieved. If you’re prescribed this medication, you will need monthly liver monitoring since this drug is very strong and can cause damage to your liver. A similar medication to Bosentan, which also stops the narrowing of your blood vessels, is Ambrisentan (Letairis).
When will there be clinical trials for ph group 3. We need meds too. Pah are living longer and longer with so many meds, but yet the trials are still all for group one. Why??