Dr. Chris Cannon discusses two studies, CHEST-1 and PATENT-1, of pulmonary hypertension patients and found that those who were taking riociguat showed significant improvement over those taking a placebo. The first study, PATENT-1, covered 443 patients and showed improvement in the six-minute walk test by an average of 36 meters and an improvement in pulmonary vascular resistance. The second clinical trial, CHEST-1, covered 261 patients and saw a 46-meter improvement in the six-minute walk test and similar improvement in pulmonary vascular resistance.
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