Could Serotonin Receptor Be Used to Treat PH in the Future?


Recent research has shown success in treating pulmonary hypertension mouse models with a serotonin receptor, which prevented the disease.

MORE: Seven facts about pulmonary hypertension you might find interesting

Mouse models treated with the small molecule SB204741 which is an antagonist of the serotonin receptor reduced the downstream activity of proteins which can potentially lead to pulmonary hypertension. After receiving treatment, some of the PH-affected cells in the mice had normalized and had lost the characteristics associated with the disease.

Although much more research in this area needs to be done before it can be used in human clinical trials, scientists are hopeful that this may be a way to treat pulmonary hypertension in the future. Find out more about this study here. 

MORE: Five tips to help you live well with pulmonary hypertension

Pulmonary Hypertension News is strictly a news and information website about the disease. It does not provide medical advice, diagnosis or treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or another qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.

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