Proteasome Inhibitors for Treating Cancer May Also Benefit PAH Patients
The rapid growth of smooth muscle cells in pulmonary arteries causes vasoconstriction and pulmonary arterial hypertension (PAH). Now, researchers found that the same drugs that inhibit cancer cell growth may also be effective in treating PAH. The study, “Inhibition of ubiquitin proteasome function prevents monocrotaline-induced pulmonary arterial…