Author Archives: Inês Martins PhD

Gene Therapy Improves PAH Symptoms in Animal Models

Gene therapy may offer a promising therapeutic approach for pulmonary arterial hypertension (PAH), according to an animal study conducted by Japanese researchers. The study “Constitutively active form of natriuretic peptide receptor 2 ameliorates experimental pulmonary arterial hypertension,” published in Molecular Therapy Methods and Clinical Development, shows…

Echocardiography May Be Easier Way to Predict Outcomes in PAH Patients

Measuring right ventricular (RV) function in patients with pulmonary arterial hypertension (PAH) using echocardiography is useful to predict patients’ prognosis, according to researchers at the Fondazione IRCCS Policlinico San Matteo in Italy. This may be of clinical relevance because echocardiography is cheaper and provides faster results than standard techniques, such as cardiac magnetic resonance…

Bosentan Improved Endothelial Function in PAH, but Not in CTEPH Patients, Study Finds

Researchers at the Nagoya University Graduate School of Medicine in Japan demonstrated that the endothelin receptor antagonist bosentan can improve endothelial dysfunction parameters in patients with pulmonary arterial hypertension (PAH), but not in patients with inoperable chronic thromboembolic pulmonary hypertension (CTEPH). The findings were published in the Pulmonary…