Author Archives: Janet Stewart, MSc

Phase 2 Trial of Levosimendan to Treat PH Linked to Specific Heart Failure Moving Forward

Plans for a Phase 2 clinical trial of levosimendan, a proposed treatment for pulmonary hypertension associated with heart failure and preserved ejection fraction, will soon be submitted to the U.S. Food and Drug Administration for approval, Tenax Therapeutics announced. In a pre-application meeting with company executives, the FDA supported the study’s proposed…

Blood-flow Measurements Could Predict Outcomes of Heart-related Pulmonary Hypertension, Study Finds

American researchers have identified three blood-flow measurements that could help doctors predict the outcomes of people whose pulmonary hypertension stems from a serious heart condition. The discovery applies to PH patients whose lung blood pressure disorder is associated with heart failure with preserved ejection fraction, or PH-HFpEF. A diagnosis of…

Phase 1 Trial for Camurus’ Long-acting CAM2043 Gets Underway

The first healthy participants have been injected with CAM2043 (treprostinil FluidCrystal Injection Depot) in a Phase 1 study assessing the treatment’s safety, tolerability, and pharmacokinetics in both single and repeated doses, the Swedish pharmaceutical company Camurus announced. CAM2043 contains treprostinil, a therapy that is effective for treating pulmonary…

Researchers Identify Risk Factors for PAH Progression in SSc-PAH patients

Male gender and lung function parameters have been identified as risk factors for progression of pulmonary arterial hypertension in patients with systemic sclerosis-PAH (SSc-PAH), a study shows. Part of the larger, multi-center, DETECT study, these results are reported in the research, “Factors associated with disease progression in early-diagnosed pulmonary arterial hypertension…