Gossamer Bio is moving toward acquiring Respira Therapeutics and its lead treatment candidate, RT234, an inhaled therapy being developed for the on-demand treatment of pulmonary hypertension (PH). The two companies entered into an option agreement that gives Gossamer the exclusive right to this acquisition within an agreed-upon…
The European Patent Office has given Tenax Therapeutics notice that it plans to grant a patent covering the use of levosimendan and its active metabolites to treat pulmonary hypertension associated with heart failure with preserved ejection fraction (PH-HFpEF), the company said. TNX-103, an oral formulation currently in Phase…
The degree of tricuspid regurgitation (TR), a cardiac abnormality detected in a heart ultrasound, may help predict the outcomes in people with pulmonary arterial hypertension (PAH), a study suggests. Those with more advanced TR were at a higher risk of death. This relationship was seen specifically in the subgroup…
Among U.S. healthcare providers who treat pulmonary arterial hypertension (PAH), a patient’s current treatment, PAH cause, and coexisting health issues are the factors that most influence their willingness to prescribe first-line combination therapy over monotherapy, according to a new study. Most clinicians said they felt a single tablet combination…
Balloon pulmonary angioplasty (BPA) led to significant clinical improvements for people with chronic thromboembolic pulmonary hypertension (CTEPH) when used as an initial therapy or after a pulmonary endarterectomy (PEA) surgery, according to a global observational study. “Our data are in line with previous reports on changes of clinical and…
The U.S. Food and Drug Administration (FDA) has approved Yutrepia, Liquidia’s inhaled dry powder formulation of treprostinil, for improving exercise capacity in people with pulmonary hypertension (PH) associated with interstitial lung disease, known as PH-ILD, and pulmonary arterial hypertension, or PAH. Yutrepia had previously held tentative approvals…
The first patient has been enrolled in a pivotal study testing the accuracy of Sensydia’s noninvasive Cardiac Performance System (CPS) for measuring cardiovascular function, including pulmonary artery pressure, a key metric used to diagnose and monitor pulmonary hypertension (PH). The multi-center, observational trial (NCT06870591) will compare CPS…
On May 5, more than 80 organizations around the world will join to raise awareness of pulmonary hypertension (PH), a serious but often under-recognized cardiovascular disease affecting more than 75 million people worldwide. World Pulmonary Hypertension Day, an annual event spearheaded by PHAEurope, also aims to promote…
A higher diameter and a faster enlargement rate of the body’s main pulmonary artery — dubbed the MPA, it carries oxygen-poor blood out of the heart toward the lungs — are independent predictors of poor outcomes among people with pulmonary arterial hypertension (PAH), a new study reports. In predicting…
Researchers in the U.S. have developed a tool to help predict mortality risk in people with chronic lung disease and pulmonary hypertension (PH). The tool, PVD-B65, accounts for risk factors related to both conditions, including age, lung disease type, PH severity, exercise capacity, and blood levels of a heart…
Corsair Pharma successfully completed preclinical studies testing its skin patch delivery system for treprostinil as a treatment for pulmonary arterial hypertension (PAH), and is now planning to launch a Phase 1 clinical trial in the next few months. That’s according to new updates from the U.S.-based company, which…
The National Organization for Rare Disorders (NORD) is seeking participants for its survey-based study Living Rare, which aims to better understand the real-world lived experiences of people in the U.S. with rare diseases. Living Rare, the first large-scale study of its kind in the U.S., seeks to capture the…
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