News

A patient treated with chemotherapy and radiation after breast cancer surgery developed pulmonary hypertension and other heart complications, according to a case study. Researchers called for doctors to watch for patients at high risk of heart damage due to cancer therapy, and recommended echocardiography for the detection of such cases. The…

The medication Adempas (riociguat) effectively improves several hemodynamic parameters in patients with pulmonary arterial hypertension (PAH), according to the Phase 3 PATENT-1 clinical trial. Results showed that the drug improved these parameters — which included pulmonary vascular resistance (PVR), right atrial pressure (RAP) and cardiac index — not only in PAH…

The European Medicines Agency (EMA) is reviewing the safety of Uptravi (selexipag) after the deaths of five patients with pulmonary arterial hypertension (PAH) who took the medicine in France. The European Union approved Uptravi for the treatment of PAH in May 2016. The EMA’s Pharmacovigilance Risk Assessment Committee (PRAC) will re-examine all…

The approved multiple-sclerosis treatment Tecfidera was seen to improve pulmonary arterial hypertension (PAH) and inhibit lung fibrosis in mice by targeting multiple signaling pathways in a recent study. The research, “Dimethyl Fumarate ameliorates pulmonary arterial hypertension and lung fibrosis by targeting multiple pathways,” was published in the journal…

Terrence Jenkins, second-year celebrity ambassador of the Pulmonary Hypertension Association (PHA), will appear in a print and digital public service ad campaign throughout 2017 to raise awareness about pulmonary hypertension (PH). Jenkins, better known as “Terrence J,” knows firsthand some of the frustrations of battling a rare disease like…

Training with an oscillatory whole-body vibration (WBV) device may improve the exercise capacity, physical performance and quality of life of patients with pulmonary arterial hypertension (PAH), according to results of a new trial. The findings were published in an article titled “Oscillatory Whole-Body Vibration Improves Exercise Capacity And Physical Performance…

Dave Merryman, a researcher at Tennessee’s Vanderbilt University, has received $6 million to develop new treatments for pulmonary hypertension and other heart diseases. His research focuses on drugs initially intended to treat rheumatoid arthritis, and knowledge from failures of weight-loss drugs. Merryman, an associate professor of biomedical engineering, is currently developing treatments for heart…

A cohort study with Chinese patients identified systemic sclerosis (SSc) as the key underlying disease that significantly worsens the clinical outcomes of patients with pulmonary arterial hypertension (PAH). The study “Clinical characteristics and survival of pulmonary arterial hypertension associated with three major connective tissue diseases: A cohort study in…

The Pulmonary Hypertension Association (PHA) will present two abstracts with data from the PHA registry, which collects information on pulmonary hypertension (PH) patients diagnosed and evaluated at PHA-accredited centers with the goal of improving their care. The presentations will be given at the American Thoracic Society meeting set for May.

Treprostinil improves exercise performance and lowers blood pressure in sickle-cell disease (SCD) patients with pulmonary hypertension (PH), a study shows. The therapy was also well tolerated by the patients, the researchers said. The findings were reported in the study “Prostacyclin-analog therapy in sickle cell pulmonary hypertension,” published…

Patients with pulmonary arterial hypertension (PAH) who took an altitude-simulation test were able to tolerate a short-term decrease in oxygen without it impacting the right side of their heart, according to a new study. The research addressed the question of whether patients with PAH can travel safely at high…

Actelion, which manufactures treatments for conditions like pulmonary arterial hypertension (PAH), will be acquired by Johnson & Johnson for $30 billion. The board of directors of both companies agreed to the transaction, said Alex Gorsky, chairman and CEO of Johnson & Johnson. “We believe this transaction offers compelling…