Posts by: Alice Melão

News, PAH News

Obese people with pulmonary arterial hypertension (PAH) are less likely than patients of normal weight to die while hospitalized, finds a study examining the so-called “obesity paradox.” The study, ... Read more

July 18, 2017July 18, 2017

Mount Sinai, Theragene Form Partnership to Move Potential PH Gene Therapy to Clinical Development

News, PH News

New York’s Mount Sinai and Theragene Pharmaceuticals have joined efforts to move a novel investigational aerosol-delivered gene therapy to treat pulmonary hypertension (PH) into a clinical development program. The new therapy, ... Read more

July 12, 2017July 12, 2017

Extended Release Formulation of PAH Therapy Ralinepag Shows Promise in Phase 1 Trial

News, PAH News

Results of a Phase 1 clinical study in healthy volunteers evaluating different formulations of Arena Pharmaceuticals’ prostacyclin receptor agonist, ralinepag, for the treatment of pulmonary arterial hypertension (PAH), showed ... Read more

July 10, 2017July 10, 2017

Adipsin Protein Is a Biomarker of PAH Associated with Systemic Sclerosis, Study Finds

News, PAH News, PH News

Elevated levels of a protein called adipsin, produced by adipose or fat tissue, was found to be associated with an increased risk of pulmonary arterial hypertension (PAH) and associated cardiovascular ... Read more

June 26, 2017June 26, 2017

Echocardiograms Can Help Identify PAH Patients at High Risk of Death, Study Reports

News

High blood pressure in the right artery makes a person with pulmonary arterial hypertension almost 2 1/2 times more likely to die than a patient with lower pressure, according ... Read more

June 9, 2017June 9, 2017

Sixty Pulmonary Hypertension Patients Receive Implanted-pump Therapy-delivery Systems

News, PAH News

Researchers implanted a long-term, intravenous therapy-delivery system consisting of internal pumps and catheters in 60 pulmonary arterial hypertension (PAH) patients, according to a clinical trial. The IV infusion system, developed ... Read more

June 6, 2017June 6, 2017

Scleroderma Does Not Impact Post-Transplant Outcomes of Pulmonary Hypertension Patients, Study Reports

News

Whether a pulmonary arterial hypertension patient has scleroderma has no bearing on the outcome of their PAH after they receive a lung transplant, a study reports. Scleroderma, also known ... Read more

June 5, 2017June 5, 2017

Depression More Likely in Chronic Thromboembolic Pulmonary Hypertension Patients, Study Finds

CTEPH News, News

People with chronic thromboembolic pulmonary hypertension (CTEPH) are more likely to have a depressive temperament, finds a Japanese study, “Depressive Status in Patients With Chronic Thromboembolic Pulmonary Hypertension” that ... Read more

May 26, 2017May 26, 2017

Minimally Invasive Endoarterial Biopsy Can Unlock Complex Molecular Mechanisms of PH Development

News, PH News

Collecting tissue samples from vessels damaged by pulmonary hypertension (PH) can help scientists learn about molecular mechanisms that cause the disease, as well as help in its, according to a new ... Read more

May 15, 2017May 15, 2017

Patients Being Enrolled for Phase 2 and 3 Trials of Bardoxolone Methyl to Treat PAH and PH

News, PAH News, PH News

Reata Pharmaceuticals is enrolling participants for two ongoing clinical trials of bardoxolone methyl as a treatment for pulmonary arterial hypertension (PAH) and pulmonary hypertension (PH) caused by an underlying interstitial ... Read more