Posts by: Alice Melão, MSc

Alice Melão, MSc

October 17, 2019October 17, 2019

Adcirca-Opsumit Combo Beneficial as First-line Treatment for Newly Diagnosed PAH Patients, Trial Shows

News, PAH News

Treatment with Adcirca (tadalafil) plus Opsumit (macitentan) can provide functional benefits and lessen symptoms in newly diagnosed patients with pulmonary arterial hypertension (PAH), results from a clinical trial show. The ... Read more

October 14, 2019October 14, 2019

Respira Reacquires Full Rights Over RT234 for As-Needed PAH Symptom Relief

News, PAH News

Respira Therapeutics has regained full worldwide research, development, and licensing rights over its inhaled medicine-device combination product, called RT234, for the treatment of pulmonary arterial hypertension (PAH). This follows the ... Read more

October 11, 2019October 11, 2019

PH Doubles Risk of Death in People with Tricuspid Regurgitation, Study Reports

News

Pulmonary hypertension contributes to markedly poorer outcomes and doubles a risk of death in people with moderate-to-severe problems in the heart’s tricuspid valve, a condition known as tricuspid regurgitation, a ... Read more

October 7, 2019November 12, 2020

Positive Data Supports Advancing Rodatristat Ethyl to Phase 2 Trials in PAH Patients, Altavant Says

News, PAH News

Oral treatment with rodatristat ethyl is safe and well-tolerated, according to results from two completed Phase 1 clinical studies in healthy volunteers. These positive results support advancing the investigational therapy ... Read more

October 3, 2019October 3, 2019

Blocking EYA3 Enzyme May Prevent Vascular Remodeling Seen in PAH, Study Suggests

News, PAH News, PH News

An enzyme involved in DNA damage processes, called EYA3, contributes to structural changes in lung blood vessels and to the progression of pulmonary hypertension (PH), according to a study in ... Read more

September 25, 2019September 25, 2019

Translate Bio Focused on Developing New Candidates to Treat PAH, Other Pulmonary Diseases

News, PAH News

Translate Bio is focusing its efforts on the development of new therapies targeting pulmonary diseases, including pulmonary arterial hypertension and cystic fibrosis, among others. In light of this, the company ... Read more

August 15, 2019

Red Blood Cell Volume May Be Marker of COPD Patients at Risk of PH, Study Suggests

News

A rise in the volume of red blood cells may help to identify people with chronic obstructive pulmonary disease who are at risk of also developing pulmonary hypertension, a study ... Read more

August 2, 2019August 2, 2019

Analyzing Exhaled Breath in Differing Positions May Be ‘Simple and Safe’ Way of Monitoring CTEPH

CTEPH News, News, PH News

Analysis of gas exhaled in differing positions, like sitting or laying flat, could be a noninvasive and simple alternative to right heart catheterization in evaluating and managing people with chronic thromboembolic ... Read more

July 31, 2019August 5, 2019

Better Risk Assessment Needed to Improve Care in PAH, International Survey Shows

News, PAH News

While physicians worldwide are conducting multi-parametric risk assessments to evaluate pulmonary arterial hypertension (PAH), they are not doing so to the extent recommended by current guidelines, results from an international ... Read more

July 18, 2019July 18, 2019

Long-term Orenitram Use Can Help PAH Patients Walk Longer Distances, Extension Trial Finds

News, PAH News

Long-term use of Orenitram led to moderate but durable, and dose dependent, improvements in exercise capacity in pulmonary arterial hypertension (PAH) patients, results from an open-label extension trial show. These findings were ... Read more