Posts by: Alice Melão

News, PAH News

A protein called RAGE was found to be an important contributor to the remodeling of blood vessels in pulmonary arterial hypertension (PAH). This is an important finding because it could ... Read more

September 12, 2018September 12, 2018

Pregnancy is High-Risk Mortality Factor Among PAH Women, ROPAC Study Reveals

News, PAH News

Pregnancy among women with heart diseases is generally safe, with just a few deaths being reported in the ROPAC registry during a 10-year period. However, pregnancy was found to ... Read more

September 5, 2018September 6, 2018

Actelion Seeks Expanded Approval of Opsumit for Treatment of CTEPH in Europe

CTEPH News, News

Actelion Pharmaceuticals has filed a request with the European Medicines Agency for the expanded approval of Opsumit (macitentan) as a treatment for adults with moderate to severe inoperable chronic ... Read more

August 24, 2018August 28, 2018

Research Study Identifies Two Proteins as Potential Biomarkers of SSc-PAH

News, PAH News, Scleroderma

Evaluation of Midkine (MDK) and Follistatin-like 3 (FSTL3) protein levels in the blood can help identify patients with systemic sclerosis-associated pulmonary arterial hypertension (SSc-PAH), researchers suggest. The study, “Serum ... Read more

August 6, 2018August 10, 2018

Bellerophon Provides Update on Clinical Development of INOpulse for Pulmonary Hypertension

News, PAH News, PH News

Bellerophon Therapeutics recently provided an update on the clinical development of INOpulse as a treatment for pulmonary arterial hypertension (PAH), as well as for pulmonary hypertension associated with chronic obstructive ... Read more

June 6, 2018June 6, 2018

Protein That Works to Regulate Blood Vessel Contraction May Lead to Better Hypertension Therapies, Study Suggests

News, PAH News, PH News

A molecular mechanism involving the tight balance between two proteins — Gal-1 and CaV1.2 — was found to regulate the behavior of blood vessel cells, directly contributing to hypertension. ... Read more

May 20, 2018May 30, 2018

EU Grants $2.91M to ATXA Therapeutics for Development of NTP42, Investigational PAH Therapy

News, PAH News

Horizon 2020, the European Union’s prestigious research and innovation program, recently awarded ATXA Therapeutics €2.5 million ($2.91 million) to support the development of ATXA’s lead therapy candidate NTP42 and help ... Read more

May 16, 2018May 16, 2018

Scottish Agency Recommends Uptravi for PAH Treatment Through National Health System

News, PAH News, PH News

Scottish patients with pulmonary arterial hypertension (PAH) can now be treated with Actelion‘s Uptravi (selexipag) through the country’s National Health System (NHS) after a positive recommendation from the Scottish Medicines ... Read more

May 14, 2018May 14, 2018

Reata Recruiting More CTD-PAH Patients for Phase 3 CATALYST Trial Testing Bardoxolone Methyl

News, PAH News, PH News

Reata Pharmaceuticals is currently recruiting participants for its Phase 3 CATALYST trial assessing the effectiveness of bardoxolone methyl in connective tissue disease-associated pulmonary arterial hypertension (CTD-PAH). After analysis of ... Read more

May 7, 2018May 7, 2018

Blocking FoxM1 Gene Seen to Prevent Vascular Remodeling and PH Progression in Mice

News, PH News

A gene called FoxM1 was seen to be an important regulator of the vascular remodeling process involved in pulmonary hypertension. It triggers the proliferation of smooth muscle cells in ... Read more

Posts by: Alice Melão

Alice Melão

Researchers Pinpoint Protein that Contributes to Blood Vessel Changes in PAH

Pregnancy is High-Risk Mortality Factor Among PAH Women, ROPAC Study Reveals

Actelion Seeks Expanded Approval of Opsumit for Treatment of CTEPH in Europe

Research Study Identifies Two Proteins as Potential Biomarkers of SSc-PAH

Bellerophon Provides Update on Clinical Development of INOpulse for Pulmonary Hypertension

Protein That Works to Regulate Blood Vessel Contraction May Lead to Better Hypertension Therapies, Study Suggests

EU Grants $2.91M to ATXA Therapeutics for Development of NTP42, Investigational PAH Therapy

Scottish Agency Recommends Uptravi for PAH Treatment Through National Health System

Reata Recruiting More CTD-PAH Patients for Phase 3 CATALYST Trial Testing Bardoxolone Methyl

Blocking FoxM1 Gene Seen to Prevent Vascular Remodeling and PH Progression in Mice

Pin It on Pinterest