Action Pharmaceuticals recently announced that the European Medicines Agency (EMA) Committee for Medicinal Products for Human Use (CHMP) has released a positive opinion on the use of Uptravi (selexipag) for the treatment of patients with a diagnosis of pulmonary arterial hypertension (PAH). Uptravi is an oral IP prostacyclin receptor agonist.
In a new study, researchers used novel cardiovascular magnetic resonance (CMR) tissue phase mapping (TPM) to determine if right ventricular disease in pulmonary hypertension (PH) patients also resulted in abnormal left ventricular functioning, discovering that left ventricular myocardial velocities are significantly abnormal in PH and also constitute independent predictors of clinical…
Increasing numbers of people in the United Kingdom are being treated for pulmonary hypertension, with a 21 percent increase in new referrals over the last five years, representing a jump t0 2,165 from 1,789 between 2010 and 2015, according to results from a national audit published by the Health and Social…
Bellerophon Therapeutics recently announced results from the final analysis of the second part of its Phase 2 clinical trial evaluating INOpulse for the treatment of pulmonary arterial hypertension (PAH), supporting the device’s continued evaluation in an upcoming Phase 3 trial. INOpulse is a proprietary device consisting of a pulsative delivery system…
People with connective tissue disease (CTD) and systemic sclerosis-associated pulmonary arterial hypertension (PAH) who are positive for anti-U1 RNP antibodies have better chances of longer-term survival. The study, “Characteristics and Survival of Anti–U1 RNP Antibody–Positive Patients With Connective Tissue Disease–Associated Pulmonary Arterial Hypertension,” was published in the journal…
The Orlando Health Heart Institute’s Pulmonary Hypertension Program was recently recognized as an accredited comprehensive care center through the Pulmonary Hypertension Association (PHA)’s accreditation program for Pulmonary Hypertension Care Centers (PHCCs). Qualifying PHCCs are either designated as a PHA-accredited Center of Comprehensive Care (CCC) or PHA-accredited Regional Clinical Program (RCP) based on…
A recent Japanese study suggested that it might be more advantageous to combine sildenafil with ambrisentan than with bosentan as a therapy for patients with pulmonary arterial hypertension (PAH). Researchers found that bosentan reduced the concentration of sildenafil in the plasma when the drugs were taken together, while sildenafil combined with ambrisentan…
Don Stevenson, also known as the Pacing Parson, is marking his 80th birthday with a 1,000-mile benefit and awareness walk for the Pulmonary Hypertension Association (PHA), a nonprofit group dedicated to extending and improving the lives of those affected by pulmonary hypertension (PH). The PHA is asking the public to support Stevenson in his efforts.
The Pulmonary Hypertension Association (PHA) recently announced the three pulmonary hypertension (PH) researchers chosen to receive its 2015 Robyn Barst Pediatric PH Research and Mentoring Awards. According to a press release, the three $50,000 award winners, whose work will also be mentored for a year, are: David Brian…
The Pulmonary Hypertension Association (PHA) announced that three more centers recently received Pulmonary Hypertension Care Center (PHCC) accreditation, raising the total number of PHA-accredited clinics to 32 across the U.S. In addition to acknowledging a high level of patient care, accreditation allows these centers to contribute to the Pulmonary Hypertension Association Registry…
Prostacyclin analogs have substantially improved pulmonary arterial hypertension (PAH) treatment, but the use of these drugs is hampered by the difficulties and risks of treating patients with continuous intravenous infusions. A new overview highlighted the development of oral prostacyclins, focusing on the drug treprostinil (Orenitram). The overview was published under the…
Patients with pulmonary arterial hypertension (PAH) carrying mutations in the bone morphogenetic protein receptor type II (BMPR2) gene have a worse prognosis, namely decreased survival rates and higher risk for lung transplantation. The findings were in a study titled “BMPR2 mutations and survival in pulmonary arterial hypertension: an…
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