Elevated Concentrations of Circulating CXCL12α Predicts Poorer Survival in Patients with Pulmonary Arterial Hypertension
Recent work in preclinical models suggests that signaling via the pro-angiogenic and pro-inflammatory cytokine, CXCL12 (SDF-1), plays an important pathogenic role in pulmonary hypertension (PH). Now a research team found that elevated concentrations of circulating CXCL12α predicts poorer survival in patients with Pulmonary Arterial Hypertension (PAH) and…