News

Bellerophon Therapeutics recently announced that INOpulse, a type of nitric oxide that helps blood vessels expand, is effective in treating Pulmonary Arterial Hypertension (PAH) based on middle-stage data from a Phase 2 trial. The US Food and Drug Administration (FDA) has issued a Special Protocol Assessment (SPA), which will help to…

Actelion Pharmaceuticals, a biopharmaceutical company developing pulmonary arterial hypertension (PAH) therapies, recently announced the presentation of further data from its pivotal Phase III GRIPHON study testing investigational PAH treatment selexipag (Uptravi) during the 2015 European Respiratory Society (ERS) Congress, which will take place in Amsterdam, Netherlands. The presentation is titled…

In a recent collaborative research project published in the PLOS one journal entitled “Risk Factors of Pulmonary Hypertension in Brazilian Patients with Sickle Cell Anemia,” researchers suggest that patients suffering from sickle cell anemia (SCA) have higher risks for developing pulmonary hypertension (PH). Sickle-cell…

Reata Pharmaceuticals has announced that it will present Phase 2 results from a trial of its investigational therapy bardoxolone methyl in treating pulmonary arterial hypertension (PAH). The study’s findings will be presented October 27, 2015 at the 2015 American College of Chest Physicians (CHEST) annual meeting in Montreal, Canada in a…

Cytori Therapeutics recently published a report of 12-month data from the Scleradec-I clinical trial studying hand dysfunction in people with scleroderma. Findings from the 12 patient trial, which was led by Dr. Brigitte Granel and Dr. Guy Magalon of the Assistance Publique des Hôpitaux de Marseille in France, is titled “Autologous…

Sunshine Heart, Inc., an early-stage medical device company focused on developing, manufacturing and commercializing the C-Pulse System for treatment of Class III and ambulatory Class IV heart failure, has announced the start of a research collaboration with Dr. Mark Slaughter and the University of Louisville to explore the technology’s potential benefits for…

A recent review, entitled “Medical treatment update on pulmonary arterial hypertension,” presents the latest research for three new drugs that have been approved by the US FDA to treat PAH. The review, which is published in Therapeutic Advances in Chronic Disease, highlights the mechanisms of action for the…

Research scientists at Bayer HealthCare AG in Germany are optimizing a new chemical inhibitor for pulmonary arterial hypertension (PAH) treatment. The team of medicinal chemists generated a library of compounds centered around inhibiting human neutrophil elastase (HNE), a key driver of inflammation in PAH. After generating molecules that successfully inhibited…