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Ascendis to Start Phase 1 Study of PAH Treatment

Ascendis Pharma A/S is beginning its phase 1 single ascending dose study on healthy participants to evaluate a potential treatment for pulmonary arterial hypertension (PAH) called TransCon Treprostinil, as announced in a press release. The investigational therapy is one of a few promising drug candidates in the clinical stage biotechnology company’s portfolio, all…

Pulmonary Arterial Hypertension Medications Studied for Drug Interactions

According to a study published by researchers at Novartis Pharma, common medications for severe pulmonary arterial hypertension interact, increasing one another’s levels when taken at the same time. However, co-administration of the medications does not appear to impact their effectiveness or increase the risk of liver problems. The study,…

Arena Pharma Begins Dosing PAH Patients with Ralinepag in Phase II Study

San Diego, California-based biopharmaceutical company Arena Pharmaceuticals, Inc. just announced they have begun dosing patients in a Phase II clinical program for ralinepag, an orally available, non-prostanoid prostacyclin (IP) receptor agonist, formulated for the treatment of pulmonary arterial hypertension (PAH). Ralinepag has performed favorably in previous preclinical and clinical…

Bristol-Myers Squibb and California Institute For Biomedical Research Collaborate On Anti-Fibrotic Therapy

A new collaboration between Bristol-Myers Squibb and the California Institute for Biomedical Research (Calibr) was announced today. The new collaboration aims to develop new small molecule anti-fibrotic therapies and includes an agreement that enables Bristol-Myers Squibb to develop, produce and commercialize the preclinical compounds that can result from this…

First Results From a National Registry for Pulmonary Hypertension in Russia

Initial results are now available from a national registry that has been established in Russia to track individuals with pulmonary hypertension (PH), including chronic thromboembolic pulmonary hypertension (CTEPH). The research was published in Russian in the journal Terapevticheskii Arkhiv (translated to Therapeutic Archive). PH is a serious disease involving high blood…

Top 14 Pulmonary Hypertension Stories of 2014

As the year 2014 comes to a close, Pulmonary Hypertension News – your reliable online source for the latest on pulmonary hypertension treatments, events, clinical trials, and research updates – brings you a concise outline of our “Top 14 Pulmonary Hypertension Stories of 2014:” No. 14 – “Pulmonary Hypertension, Other Lung…

Pulmonary Arterial Hypertension in the US: How Much Does it Cost?

Pulmonary arterial hypertension (PAH)  is a rare condition characterized by high blood pressure of the lung arteries. It costs a great deal in human life lost and life impairment, but how much money is it costing to treat? A recent study published in BMC Health Services Research attempted to answer…