News

A new study, entitled “The Sphingosine Kinase 1 / Sphingosine-1-Phosphate Pathway in Pulmonary Arterial Hypertension” conducted at University of Illinois’s College of Medicine, at Chicago, published in the American Journal of Respiratory and Critical Care Medicine, by Dr. Jiwang Chen, research assistant professor of critical care…

A new study published in August’s issue of Cardiovascular Research, entitled “Ranolazine prevents INaL enhancement and blunts myocardial remodeling in a model of pulmonary hypertension” suggests ranolazine (RAN) as a potential therapeutic agent in the treatment of PAH pathology. Pulmonary arterial hypertension (PAH) is a result of…

Pulmonary hypertension is a life-threatening, progressive disease that, to this day, is still incurable. Recently, a team of researchers turned to nature for answers, experimenting with extracting a protective enzyme from plant leaves that may hold the key to making a novel treatment work. Lead author and assistant…

The Maryland chapter of the Pulmonary Hypertension Association (PHA) recently announced that it is hosting a presentation on Emergency Preparedness for Pulmonary Hypertension Patients, via their Facebook page, which is taking place on Tuesday, September 23rd at 10 pm. The event is designed to help educated patients on…

Every Breath Counts: Idiopathic Pulmonary Fibrosis, a documentary to mark Pulmonary Fibrosis Awareness Month, will air on the Discovery Channel on September 13th and 27th at 8:00 am ET/PT. Supported by Boehringer Ingelheim Pharmaceuticals, Inc. and created together with the Pulmonary Fibrosis Foundation and the Coalition for Pulmonary Fibrosis, the…

Pulmonary Arterial Hypertension (PAH) is a life-threatening disease in which endothelial dysfunction, vasoconstriction in small pulmonary arteries, dysregulated proliferation of vascular cells, and dysregulated inflammatory signaling leads to pulmonary arterial obstruction increasing pulmonary vascular resistance and resulting in right ventricular failure. Different types of treatments for PAH exist that can…

Overwhelmingly positive results of Mast Therapeutics, Inc.‘s Phase 2 clinical trial of AIR001 (sodium nitrite, or Aironite®) inhalation solution for pulmonary arterial hypertension will lead to the company’s pursuit of additional Phase 2 trials in the near future. All doses of AIR001 were well-tolerated by patients and provided improvements…

Findings collected during more than two years confirming the safety and efficacy of Bayer’s Adempas® (riociguat) in treating either inoperable or persistent/recurrent chronic thromboembolic pulmonary hypertension (CTEPH), and patients with pulmonary arterial hypertension (PAH) were recently presented at the European Respiratory Society (ERS) Congress. Riociguat is the first member of…

When Gilead Sciences, Inc. initiated a clinical trial for first-line combination therapy for pulmonary arterial hypertension treatment, the company felt that their ambitious approach to developing a new, viable therapy for the disease was worthy of the clinical trial name “AMBITION.” Now, according to a…

Photo Caption: “The Process is the product” – Pluristem’s 3D expansion technology allows for the production of different PLX cell products. Photo credit: Pluristem Therapeutics Inc. Haifa, Israel based Pluristem Therapeutics Inc. a drug developer specializing in placenta-based cell therapy products, has announced that licensee partner United Therapeutics…

Pulmonary hypertension occurs when there is an abnormal buildup of blood pressure pumped from the heart to the pulmonary vasculature, eventually causing the vessels in the lungs to constrict and lead to a reduction in blood oxygenation. At present, this deadly disease remains incurable, with a 68 percent chance…

Pulmonary hypertension is a condition caused by increased pressure in the pulmonary arteries. In advanced cases, its symptoms (shortness of breath, tiredness, chest pain) worsen and may limit all physical activity. Now, researchers from University of California, Los Angeles have developed a successful treatment to rescue advanced forms of…