News

Reata Begins Enrollment For PAH – LARIAT Phase 2 Study Examining Bardoxolone Methyl for Treating Pulmonary Arterial Hypertension

Irving, Texas based Reata Pharmaceuticals, Inc. has enrolled the first patient in a Phase 2 dose ranging study examining the safety, tolerability, and efficacy of bardoxolone methyl in patients with pulmonary arterial hypertension (PAH). PAH is a life-threatening disease involving endothelial dysfunction, vasoconstriction in small pulmonary arteries, aberrant…

SteadyMed Establishes New Agreement With Bespak Europe for PAH Treatment

SteadyMed Therapeutics, a pharmaceutical company focused on developing drugs to treat underserved medical needs in orphan and high value disease states, recently announced a development and manufacturing agreement with Bespak Europe, a Consort Medical company and supplier of drug delivery devices for injectable and inhaled products. The two companies will join efforts to produce…

Nutritional Supplement NAC Studied as PH Treatment

The nutritional supplement N-acetylcysteine (NAC) may have immunomodulatory and cardioprotective properties, which can potentially benefit pulmonary hypertension patients, according to the recent study “N-acetylcysteine improves established monocrotaline-induced pulmonary hypertension in rats,” conducted by Dr. Marie-Camille Chaumais, at the University of Paris-Sud, College of Pharmacy, France. As the pathophysiology of pulmonary arterial hypertension…

Updated PAH Guidelines Released By The American College of Chest Physicians

The American College of Chest Physicians (CHEST) has announced updates to its Pulmonary Arterial Hypertension guidelines in the online publication of “Pharmacological Therapy for Pulmonary Arterial Hypertension in Adults: CHEST Guideline” (Chest. 2014;145(5):1055-1063. doi:10.1378/chest.13-1864) in the journal CHEST. Pulmonary arterial hypertension (PAH) is a rare form of pulmonary…