When given alone or in combination with other therapies, Opsumit (macitentan) leads to clinically meaningful improvements in right heart function in people with pulmonary arterial hypertension (PAH), according to data from a final analysis of a Phase 4 trial. Findings were announced in the presentation “…

After demonstrating an ability to deliver top-shelf care to patients with pulmonary hypertension (PH), four sites have been added to the Pulmonary Hypertension Association’s (PHA) network of Centers of Comprehensive Care (CCC). The newly accredited centers are the Cleveland Clinic in Ohio, Tufts…

Like many rare disease charities, the Pulmonary Hypertension Association (PHA) was formed in 1991 by four women sitting around a kitchen table in Florida, hoping for a cure. Yet the PHA is probably the only patient advocacy group that actually preserved its original kitchen table and chairs — and made…

Riociguat increases the risk of death and serious adverse events in people with pulmonary hypertension (PH) associated with idiopathic interstitial pneumonia (IIP), and should not be prescribed to those patients, final results of a Phase 2 study show. The study, “Riociguat for idiopathic interstitial pneumonia-associated pulmonary hypertension…

A new analysis of Actelion‘s GRIPHON clinical trial indicates that Uptravi (selexipag) tablets reduce the risk of disease complications or death in patients with pulmonary arterial hypertension (PAH), regardless of when treatment begins. However, its effectiveness was greater if started sooner after diagnosis. The data was presented at…

Treatment with Opsumit (macitentan) can significantly improve the heart’s right ventricular function, reverse cardiac tissue remodeling, and reduce pulmonary vascular resistance (PVR) in patients with pulmonary arterial hypertension (PAH), preliminary results from a Phase 4 clinical trial show. The most recent data from the Phase 4 REPAIR trial (…

This podcast series, created and produced by phaware, is being offered as a regular guest feature on Pulmonary Hypertension News to bring the voices and life experiences of PH patients, family members, caregivers, healthcare specialists, and others to our readers. You may listen to the podcast directly, or read it…

This podcast series, created and produced by phaware, is being offered as a regular guest feature on Pulmonary Hypertension News to bring the voices and life experiences of PH patients, family members, caregivers, healthcare specialists, and others to our readers. You may listen to the…

A recent article that presented case studies of three patients with rheumatoid arthritis-associated pulmonary hypertension (PH), highlights the diversity of the underlying causes of the disease, and emphasizes the importance of diagnosing it early. The study “Rheumatoid arthritis associated pulmonary hypertension: Clinical challenges reflecting the diversity of pathophysiology”…

A molecule linked to pulmonary hypertension (PH) in earlier studies failed to serve as a biomarker of disease severity or prognosis in a new study, which analyzed blood levels of the factor in people with various types of lung hypertension. Although the molecule, known as Ang-1, does not appear to be a…

The Pulmonary Hypertension Association (PHA) is organizing a series of events, called “PHA on the Road: PH Patients and Families Education Forum,” to give the pulmonary hypertension (PH) community a free, day-long platform through which to network with other patients, medical professionals, and PH experts. Two upcoming…

The European Medicines Agency (EMA), the European Union parallel to the U.S. Food and Drug Administration (FDA), advised that the therapy Adempas (riociguat) should not be prescribed to patients with PH associated with idiopathic interstitial pneumonia (PH-IIP). According to a press release, EMA’s recommendation was supported by results of a Phase 2…