2. Endothelin receptor antagonists.
Endothelin is the substance that causes the blood vessels to narrow. Endothelin receptor antagonists are medications that reverse this effect. Bosentan (Tracleer) is one of these medications. While taking it, pulmonary hypertension patients may see their energy levels improved and their symptoms relieved. If you are prescribed this medication, you will need monthly liver monitoring since the very strong drug can cause liver damage. A similar medication to Bosentan, which also stops the narrowing of your blood vessels, is ambrisentan (Letairis).
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