Author Archives: Alice Melão, MSc

Bellerophon Provides Update on Clinical Development of INOpulse for Pulmonary Hypertension

Bellerophon Therapeutics recently provided an update on the clinical development of INOpulse as a treatment for pulmonary arterial hypertension (PAH), as well as for pulmonary hypertension associated with chronic obstructive pulmonary disease (PH-COPD) and interstitial lung disease (PH-ILD). INOpulse is an inhaled nitric oxide treatment being developed to reduce…

Protein That Works to Regulate Blood Vessel Contraction May Lead to Better Hypertension Therapies, Study Suggests

A molecular mechanism involving the tight balance between two proteins — Gal-1 and CaV1.2 — was found to regulate the behavior of blood vessel cells, directly contributing to hypertension. This finding provides new insights into the underlying processes that trigger arterial contraction and hypertension, and its researchers suggest that a…

Bellerophon Is Advancing Its PH Treatment INOpulse Through Clinical Trials

Bellerophon Therapeutics is advancing the clinical trials program of its inhaled INOpulse nitric oxide therapy for pulmonary hypertension (PH) associated with several lung diseases. The company is developing INOpulse for patients with pulmonary arterial hypertension (PAH), PH associated with chronic obstructive pulmonary disease (COPD), and PH linked to interstitial lung…

British Scientists Developing Advanced Pulmonary Hypertension Imaging

Computer software combined with artificial intelligence can generate advanced imaging techniques for serious diseases such as pulmonary hypertension (PH), improving healthcare, British scientists say. This was the focus of a workshop on digital radiology at Imperial College Academic Health Science Centre (AHSC) that brought together medical researchers, computer scientists, mathematicians…