Author Archives: Iqra Mumal, MSc

Sarcoidosis-associated Pulmonary Hypertension Is Linked to a Poor Prognosis

Pulmonary hypertension in patients with sarcoidosis is associated with poor prognosis, despite treatment with a targeted therapy, a new study shows. The study “Management and long-term outcomes of sarcoidosis-associated pulmonary hypertension,” was published in the European Respiratory Journal. Patients with sarcoidosis frequently develop pulmonary hypertension. In…

PDE5 Blocker May Be an Effective Therapy for Early PH After Heart Attack, Study Suggests

Blocking the enzyme phosphodiesterase 5 (PDE5) is a potential new therapeutic strategy to treat early pulmonary hypertension (PH) in patients who have had a heart attack, a study suggests. The research, “Pulmonary vasodilation by phosphodiesterase 5-inhibition is enhanced and nitric oxide-independent in early pulmonary hypertension after myocardial infarction,”…

Estrogen Inhibitors Can Prevent and Treat PAH in Mice, Vanderbilt Study Finds

Estrogen inhibitors may treat pulmonary vascular disease by correcting metabolic defects in women with pulmonary arterial hypertension (PAH), say researchers at Nashville’s Vanderbilt University. Their study,“Oestrogen inhibition reverses pulmonary arterial hypertension and associated metabolic defects,” appeared in the European Respiratory Journal. Most people with hereditary PAH have mutations…