Author Archives: Marta Figueiredo PhD

Adempas Safe in PAH Patients Over Long Term, Real-world Study Shows

Long-term treatment with Bayer’s Adempas (riociguat) was safe and well-tolerated in people with pulmonary arterial hypertension (PAH), according to data from the real-world EXPERT study. These findings from clinical practice were consistent with those reported in previous clinical trials, supporting the therapy’s favorable safety profile. Data from EXPERT…

INOmax Use Aids Premature Babies with PH, Phase 4 Study Shows

Mallinckrodt Pharmaceuticals’ INOmax (nitric oxide) gas improves oxygenation in premature newborns with pulmonary hypertension (PH) at least as effectively as it does  in term and near-term babies, data from a Phase 4 observational study show. These findings, from a second planned interim study analysis (at 75% enrollment),…

Riociguat Not Recommended for Patients with PH Associated with IIP

Riociguat increases the risk of death and serious adverse events in people with pulmonary hypertension (PH) associated with idiopathic interstitial pneumonia (IIP), and should not be prescribed to those patients, final results of a Phase 2 study show. The study, “Riociguat for idiopathic interstitial pneumonia-associated pulmonary hypertension…

Actelion’s Opsumit Shows Promise as Treatment for Portopulmonary Hypertension, Trial Results Show

Actelion Pharmaceuticals’ Opsumit (macitentan) may be a potential therapy for portopulmonary hypertension, according to positive results from a Phase 4 clinical study. The data was presented at the European Respiratory Society (ERS) meeting, held Sept. 15-19 in Paris. The development of pulmonary arterial hypertension (PAH) in association with…