Author Archives: Marta Figueiredo PhD

Arterial Stiffness Early Marker of CTEPH After Embolism

In people experiencing a pulmonary embolism, higher-than-normal arterial stiffness at the time of hospital discharge increased the risk of pulmonary arterial hypertension (PAH) when evaluated one month later, according to a study in Italy. Given that this patient population is at risk of chronic thromboembolic pulmonary hypertension…

CIT GAP Funds Invests in OxiWear Device for PH Patients

The Center for Innovative Technology (CIT) GAP Funds has invested in OxiWear and its ear-wearable device designed to continuously monitor blood oxygen levels in people with pulmonary hypertension (PH) and alert them when levels fall below safe thresholds. Oxiwear is expected to help patients get the help they…

Research Sheds Light on Potential Immune Changes in IPAH

A combination of lung injury and increased activation of B-cells — immune cells responsible for antibody production — was sufficient to promote symptoms of pulmonary hypertension (PH) in mice, a study shows. In addition, increased B-cell activation and higher levels of immune cells known to promote antibody production also were…

Text-based Intervention Helped Increase Physical Activity

A three-month unsupervised health intervention based on a commercial activity tracker and motivational texts significantly increased daily step counts and improved quality of life in adults with pulmonary arterial hypertension (PAH), according to data from a single-center trial in the U.S. Since physical activity has been shown to…

KER-012 Found to Prevent Increased Scarring in Rat Model of PAH

Keros Therapeutics’ experimental therapy KER-012 prevented increases in the levels of markers for inflammation, fibrosis (scarring), and heart damage in a rat model of pulmonary arterial hypertension (PAH), a study shows. “We believe that the current study supports that KER-012 has the potential to treat PAH in patients without…

Tyvaso Becomes 1st PH-ILD Treatment Approved in US

Tyvaso (inhaled treprostinil) has become the first treatment approved in the U.S. for people with pulmonary hypertension associated with interstitial lung disease (PH-ILD). The U.S. Food and Drug Administration (FDA) approved Tyvaso, developed by United Therapeutics, to improve exercise ability in PH-ILD patients, the company said. “The…

Adempas Safe in PAH Patients Over Long Term, Real-world Study Shows

Long-term treatment with Bayer’s Adempas (riociguat) was safe and well-tolerated in people with pulmonary arterial hypertension (PAH), according to data from the real-world EXPERT study. These findings from clinical practice were consistent with those reported in previous clinical trials, supporting the therapy’s favorable safety profile. Data from EXPERT…