PatrĂ­cia Silva, PhD, director of science content —

PatrĂ­cia holds a PhD in medical microbiology and infectious diseases from the Leiden University Medical Center, Netherlands, and completed a postdoctoral research fellowship at the Instituto de Medicina Molecular, Lisbon, Portugal. Her work in academia was mainly focused on molecular biology and the genetic traits of infectious agents such as viruses and parasites. PatrĂ­cia earned several travel awards to present her work at international scientific meetings. She is a published author of several peer-reviewed science articles.

Articles by PatrĂ­cia Silva

PHA Reveals Encouraging Results From National Call-In Day

The Pulmonary Hypertension Association (PHA) has shared the results of its recent National Call-In Day, reporting that the event was a major success thanks to the participation of the pulmonary hypertension community. The National Call-In Day took place on April 16th as part of an initiative to encourage PH advocates to call Congressional members and…

PHA Awards 12 PH Community Service Projects

The Pulmonary Hypertension Association (PHA) has awarded 12 community activists with the 2015 Tom Lantos Innovation in Community Service Award. The awardees, who will receive $5,000 each, are heading projects that are committed to raising awareness about pulmonary hypertension (PH). The Tom Lantos Innovation in Community Service Awards were created…

PH Association Creates Social Media Pin to Celebrate the World Pulmonary Hypertension Day Tomorrow, May 5

The Pulmonary Hypertension Association (PHA) recently announced in a press release that it will take the lead in a global effort to educate the general public about pulmonary hypertension on May 5, marked as World Pulmonary Hypertension Day. Pulmonary hypertension (PH) is a rare, debilitating, life-threatening condition characterized by an increase of blood…

PHA Accredits RI Hospital Pulmonary Hypertension Center

The Pulmonary Hypertension Association (PHA) has granted the PHA-accredited Center of Comprehensive Care (CCC) designation to the Pulmonary Hypertension Center at Rhode Island Hospital, making it one of the first centers of its type to receive the status in the country. The accreditation is given to centers for their excellency in…

Ascendis Pharma Reveals Results of Phase 1 Study of Pulmonary Arterial Hypertension Therapy TransCon Treprostinil

Ascendis Pharma A/S, a clinical stage biotechnology company focused on creating drug candidates by improving existing drugs, recently announced results from its Phase 1 single ascending dose trial of TransCon Treprostinil, which produced a dose-dependent increase in plasma treprostinil levels. However, results from the study showed that the tolerability of treprostinil…

Elevated Concentrations of Circulating CXCL12α Predicts Poorer Survival in Patients with Pulmonary Arterial Hypertension

Recent work in preclinical models suggests that signaling via the pro-angiogenic and pro-inflammatory cytokine, CXCL12 (SDF-1), plays an important pathogenic role in pulmonary hypertension (PH). Now a research team found that elevated concentrations of circulating CXCL12α predicts poorer survival in patients with Pulmonary Arterial Hypertension (PAH) and…

Reata’s PAH Therapy Granted Orphan Drug Designation

Irving, Texas-based Reata Pharmaceuticals, Inc. has been granted orphan drug designation from the U.S. Food and Drug Administration (FDA) for its pulmonary arterial hypertension (PAH) treatment. The FDA’s Office of Orphan Products Development (OOPD) awarded the designation to bardoxolone methyl due to its novel…


A Conversation With Rare Disease Advocates