Mast Therapeutics announced that positive interim data from its ongoing Phase 2a clinical trial of AIR001 (sodium nitrite, or Aironite) inhalation solution for the treatment of patients with pulmonary hypertension (PH) have been published in the Journal of Clinical Investigation (JCI). The open label, Phase 2a clinical trial (NCT01431313) is evaluating…
The Pulmonary Hypertension Association (PHA) has started a social media video campaign, A Heart Cures, asking people to make and share 10- to 30-second videos of themselves giving thanks to loved ones or strangers for little acts of kindness and support. Posted videos will run through November, which is both…
Gilead Sciences reported that selonsertib (also known as GS-4997), an investigational treatment for pulmonary arterial hypertension (PAH), did not achieve the primary endpoint in an analysis of ARROW, a Phase 2 clinical trial (NCT02234141) evaluating the drug’s efficacy, safety and tolerability. The company also reported top-line data from two other…
The Pulmonary Hypertension Association (PHA) is planning a series of events for November, Pulmonary Hypertension Awareness Month, including a daylong focus on chronic thromboembolic pulmonary hypertension (CTEPH), a form of pulmonary hypertension (PH) that results from blood clots in the lungs. Events planned for CTEPH Awareness Day, Nov. 15, include promoting information about the two…
Elsevier announced that it is expanding its work with the American College of Chest Physicians (CHEST) to provide CHEST members with detailed and interactive eLearning programs that address their specialities, including pulmonary arterial hypertension (PAH) and chronic obstructive pulmonary disease (COPD). Elsevier is a provider of scientific, technical and medical information products, and the…
The Pulmonary Hypertension Association (PHA) is organizing a series of events, called “PHA on the Road: PH Patients and Families Education Forum,” to give the pulmonary hypertension (PH) community a free, day-long platform through which to network with other patients, medical professionals, and PH experts. Two upcoming…
The Pulmonary Hypertension Association (PHA) is urging the U.S. Senate to support the Pulmonary Hypertension Research and Diagnosis Act of 2016 (S. 3361), introduced this week by the Sen. Bob Casey and aiming to speed the development of new treatments and improve the care of people with pulmonary…
The use of nitrite salts for the treatment of cardiovascular conditions, such as pulmonary hypertension, is now patented by the U.S. Patent and Trademark Office (USPTO). The new patent (US 20060182815 A1) was awarded to Gordon G. Power with Loma Linda University, and a team of investigators from several other universities,…
Rats with induced pulmonary hypertension (PH) and all its symptoms that were then treated with a modified strain of Lactobacillus, a probiotic bacteria engineered to produce a specific oral peptide, showed a reversal in those symptoms: reduced blood pressure, reduced heart wall thickness, and improved heart contractility. The results were recently…
At the upcoming Evening of Hope Gala, the California chapter of the Pulmonary Hypertension Association (PHA) will recognize two pioneers in the field of pulmonary hypertension (PH): Jean-Paul Clozel, MD, a cardiologist who is the chief executive officer the of the biopharmaceutical company Actelion, and his wife Martine Clozel, MD, a pediatrician who…
Symple Surgical (SSI), a start-up medical device company, announced that it has entered into a development agreement with a confidential partner to advance its microwave ablation technology, for the treatment of hypertension and potentially other conditions, including pulmonary hypertension. The unnamed partner, it said in a press release, has with a long-standing market leadership…
Researchers identified two new drugs, both signaling inhibitors, that could aid in the treatment of pulmonary hypertension (PH) by altering vessel stiffness and its downstream control of metabolism. Their work also suggests that a previously unknown link exists between vessel hardening and energy production in the disease. The study, “Vascular…
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