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Vanderbilt Researcher Receives $6M to Study Pulmonary Hypertension, Other Heart Diseases

Dave Merryman, a researcher at Tennessee’s Vanderbilt University, has received $6 million to develop new treatments for pulmonary hypertension and other heart diseases. His research focuses on drugs initially intended to treat rheumatoid arthritis, and knowledge from failures of weight-loss drugs. Merryman, an associate professor of biomedical engineering, is currently developing treatments for heart…

Tracleer and Ventavis Combo as Initial Therapy Seen to Benefit Patients with Advanced PAH

An initial combination treatment with Tracleer (bosentan) and Ventavis (iloprost, inhalation solution) dramatically improved exercise capacity and clinical function in patients with pulmonary arterial hypertension (PAH), compared to treatment with either of those medications alone. The study, “Treatment of pulmonary arterial hypertension using initial combination therapy of…

Interferon Therapy Seen as Notable Risk Factor for Pulmonary Arterial Hypertension

Pulmonary arterial hypertension (PAH) is a rare complication in hepatitis C or multiple sclerosis patients using interferon α or β therapy, but still one that’s substantially more common in these people than in the general population, suggesting a link between the therapy and PAH, researchers reported. Type I interferons, including interferon α and β, are naturally occurring compounds in the body,…