The INOpulse portable oxygen provider widened blood vessels, lowered blood pressure and increased exercise capacity in pulmonary hypertension patients with idiopathic pulmonary fibrosis (PH-IPF), according to a study. Bellerophon Therapeutics, which developed the device, reported the results at the American Thoracic Society International Conference in Washington. It also discussed plans for…
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The Pulmonary Hypertension Association has accredited three more regional clinics that have demonstrated an ability to deliver high-quality care to pulmonary hypertension (PH) patients. The three are the French Hospital Medical Center’s Central Coast Pulmonary Hypertension Center in San Luis Obispo, California; Sentara Norfolk General Hospital’s Pulmonary…
Two pulmonary arterial hypertension experts will speak to investment professionals at a gathering in New York this week that Arena Pharmaceuticals is holding. Arena will also discuss ralinepag (APD811), a treatment it is developing for PAH, at the event on May 25. The experts are Dr. Lewis Rubin, an emeritus professor…
Tracleer, which improves pulmonary arterial hypertension patients’ exercise capability, may decrease the effectives of two other PAH treatments, Revatio and Adcirca, according to a study. One of the problems with treatment combinations is that some of the therapies can affect the others’ ability to do their work. This appears to be…
The prevalence of pregnant women with heart disease rose by 24 percent over a 10-year period, according to a study, “National Trends and In-Hospital Outcomes in Pregnant Women With Heart Disease in the United States,” that appeared in the American Journal of Cardiology. Researchers at New York’s Stony Brook…
Bellerophon Therapeutics recently offered an update on the company’s INOpulse system, as part of its first quarter 2017 financial report. The system is in clinical testing as a therapy for three types of pulmonary hypertension. The Phase 3 INOpulse program for pulmonary arterial hypertension (PAH) has been modified to speed up its clinical development.
Patient enrollment is complete in a Phase 2 clinical trial of ubenimex as an add-on to standard therapy for pulmonary arterial hypertension (PAH), according to ubenimex’s developer, Eiger BioPharmaceuticals. Sixty-one patients at 45 sites in the United States and Canada have been enrolled in the LIBERTY trial (NCT02664558). The randomized, double-blind,…
Reata Pharmaceuticals is enrolling participants for two ongoing clinical trials of bardoxolone methyl as a treatment for pulmonary arterial hypertension (PAH) and pulmonary hypertension (PH) caused by an underlying interstitial lung disease. Bardoxolone methyl belongs to a class of small molecules that target an important transcription factor called Nrf2.
Lung disease is one of the main causes of American deaths, second only to heart disease. While some lung diseases are genetic and unavoidable, following a healthy lifestyle and avoiding lung irritants can help protect you from developing many of them. We’ve put together a list of tips to help lower your risk of developing a…
Pulmonary hypertension (PH) only rarely affects children born with the genetic condition incontinentia pigmenti, illustrating that researchers lack insights into how molecular abnormalities translate into problems in the heart and lungs. A case report by researchers from Saudi Arabia’s King Abdullah International Medical Research Center in Riyadh illustrates the condition, and…
Third Pole has won a Johnson & Johnson Innovation award for a lighter device that provides an unlimited supply of nitric oxide (NO) to patients with pulmonary hypertension (PH) and other respiratory conditions. The beauty of Third Pole’s Electric NO device, which won Johnson Innovation’s JLABS @ M2D2 QuickFire Challenge,…
The new pulmonary endarterectomy (PEA) surgery simulator — a 3D device developed by the National Research Council of Canada with support from Bayer — could potentially improve the lives of thousands of Canadians with chronic thromboembolic pulmonary hypertension (CTEPH). The first-of-its-kind simulator will allow surgeons to train more efficiently for surgery to treat CTEPH, a…
