Liraglutide, a drug used to treat type 2 diabetes (brand name, Victoza) and obesity (brand name, Saxenda), is currently being evaluated as a possible therapy for Parkinson’s disease. Now, a new study suggests that liraglutide may also be quite effective in treating pulmonary arterial hypertension (PAH). The study, “Liraglutide prevents and reverses monocrotaline-induced…
Unfortunately, there is still no known cure available for pulmonary hypertension, but research has been evolving and doctors and scientists have been discovering some new ways to approach the lung condition. You might be interested in reading more about Uptravi (selexipag) as a treatment for PH. According to…
The French biotechnology company Mifcare recently announced, in a press release, that their lead anti-inflammatory compound, MFC1040 has been shown to be efficient in a second animal model of pulmonary arterial hypertension (PAH).
Serena Lawrence, a young Canadian living with pulmonary hypertension (PH), has launched an online petition to raise public consciousness of, and draw government attention to, PH in Canada. Upon receiving her diagnosis of Stage 3-4 PH in 2013 at age 25, just three months after first showing her…
A new study published in the scientific journal Respiration suggests that bronchoscopy with transbronchial and endobronchial biopsy and transbronchial needle aspiration are safe in patients with echocardiographic evidence of PH.
Both patients newly diagnosed with pulmonary arterial hypertension (PAH) and animal models of the disease show increased activity of a molecular pathway, known as NNMT-MNA (Nicotinamide N-methyltransferase and 1-methylnicotinamide), which is involved in metabolic and inflammatory reactions. The researchers behind the study, “Activation of the nicotinamide N-methyltransferase (NNMT)-1-methylnicotinamide (MNA) pathway in…
SteadyMed announced that it recently completed the manufacturing of required batches of its drug candidate Trevyent, designed to treat pulmonary arterial hypertension (PAH). The work will allow the company to evaluate the therapy’s shelf-life in advance of submitting a New Drug Application to the U.S. Food and Drug Administration (FDA) early next year.
Patients with pulmonary arterial hypertension (PAH) who fail to benefit from treatment with phosphodiesterase 5 inhibitors (PDE5i) may safely switch to Adempas (riociguat), according to the final results of a clinical trial, which showed that Adempas improved their health. The results were presented at the European Respiratory Society (ERS) International…
An electronic nose, or “e-nose,” that can detect the presence of pulmonary arterial hypertension (PAH) was created by researchers at the Université Paris-Saclay in partnership with the Technion Israel Institute of Technology. The e-nose device makes use of the fact that PAH has a marked olfactory signature, with a specific…
A new study published in the Journal of the American Heart Association reports that, in people with pulmonary hypertension (PH), females, middle-aged patients, and those with chronic diseases have an increased risk of mortality. Most current knowledge comes from small-scale or specialized studies. This is the first Taiwan nationwide…
Patients with chronic thromboembolic pulmonary hypertension (CTEPH) who are successfully treated with pulmonary endarterectomy (PEA) may be at increased risk of having low levels of oxygen in the blood due to severe pulmonary arteriopathy, a condition characterized by pulmonary artery remodeling, according to a study from Chiba University in Japan. The…
Symple Surgical (SSI), a start-up medical device company, announced that it has entered into a development agreement with a confidential partner to advance its microwave ablation technology, for the treatment of hypertension and potentially other conditions, including pulmonary hypertension. The unnamed partner, it said in a press release, has with a long-standing market leadership…
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