News

Experimental PAH Therapy to Be Tested in New Clinical Trial

Eiger BioPharmaceuticals, Inc., a clinical-stage biopharmaceutical company that develops and commercializes drugs for the treatment of orphan diseases and conditions with ineffective current treatments, announced a new license agreement with a leading Japanese pharmaceutical company, Nippon Kayaku. Eiger BioPharmaceuticals aims to develop Nippon Kayaku’s therapeutic drug Bestatin™ (ubenimex) for the treatment of pulmonary…

Associated Conditions in PH Found To Affect Prognosis

A new study by Romanian and Belgian scientists sheds light on specific conditions associated with pulmonary hypertension (PH), and which of those conditions are associated with a better prognosis for survival. The report, titled “Is Right Ventricular Remodeling in Pulmonary Hypertension Dependent on Etiology? An Echocardiographic Study,”appeared in the…

AHS/ATA Develop New Pediatric Pulmonary Hypertension Guidelines

The American Heart Association (AHA) and American Thoracic Society (ATS) have issued new guidelines pertaining to Pediatric Pulmonary Hypertension. The revisions come as a result of collaboration between the agencies and were developed in a joint effort by an interdisciplinary team of 27 experienced clinicians and clinician-scientists in a review…

Study Tracks Pulmonary Hypertension Patients Through Orthopedic Surgery

Recently published research reveals that orthopedic (musculoskeletal) surgery in patients with pulmonary hypertension (PH), while challenging, is feasible and offers decent outcomes even in severe stages of the disease, provided proper care is given. The paper entitled “Perioperative management of patients with severe pulmonary hypertension in major orthopedic surgery: experience-based recommendations“ was published in…

New Tool Assesses Right Ventricular Dysfunction in PH, Congenital Heart Disease and Cardiomyopathy

Right ventricular (RV) dysfunction is a characteristic of several disorders such as pulmonary hypertension, congenital heart disease and cardiomyopathy, making RV function evaluation key to effective prognosis and diagnostic value in such disorders. However, diagnosis through RV function is challenging due to anatomical configuration of the RV. Right ventricular outflow tract (RVOT)…

Cell-based Therapy Tested in First PHS Patient Study

In a new study entitled “Endothelial NO-Synthase Gene-Enhanced Progenitor Cell Therapy for Pulmonary Arterial Hypertension: The PHACeT Trial,” researchers performed the first human trial to investigate the therapeutic potential of endothelial progenitor cells in repairing the damaged vessels in pulmonary arterial hypertension patients who have failed to…

INOmax Vasodilator Device For Pulmonary Hypertension Approved In Australia And Japan

Dublin, Ireland, based biopharmaceutical company Mallinckrodt plc reports that its INOmax (nitric oxide) vasodilator inhalation device has received regulatory approval in Australia and Japan for treating pulmonary hypertension in conjunction with heart surgery. The Australian Therapeutic Goods Administration (TGA) has approved INOmax for peri- and post-operative pulmonary hypertension…

PHA Celebrates PH Awareness Month with Major Campaign

November is Pulmonary Hypertension Awareness Month and the Pulmonary Hypertension Association (PHA) is planning to launch a new public service campaign called Heart2CurePH that promises to increase understanding of pulmonary hypertension (PH). The worldwide educational campaign will include TV, radio, and place-based and print materials, while anyone on social media can…

Pulmonary Hypertension Gets New Treatment in Helpful Comic Book

The latest comic book in a peer-reviewed series on pulmonary hypertension (PH) has been launched by Medikis, with the collaboration of the Imperial College Healthcare NHS Trust. The comic book, entitled Medikidz Explains Pulmonary Arterial Hypertension, aims to increase knowledge about the life-threatening disease among younger audiences.

GSK’s Application to Expand PAH Drug Volibris’ (ambrisentan) Therapeutic Indication as Combined Treatment Receives Positive CHMP Opinion

GlaxoSmithKline (GSK) recently announced that the European Medicine Agency’s (EMA) Committee for Medicinal Products for Human Use (CHMP) has released a positive recommendation for its application to expand the existing therapeutic indication for pulmonary arterial hypertension (PAH) combination treatment Volibris® (ambrisentan) — a selective endothelin type-A receptor antagonist. The therapy is currently approved…


A Conversation With Rare Disease Advocates