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Mapping Successful PAH Treatments Using Blood Signatures

In a perfect world, equivalent responses to treatments from patients with pulmonary hypertension would make all treatment outcomes predictable and highly effective. In reality, this is not the case. However, distinguishing subtypes of pulmonary arterial hypertension can at least improve treatment outcomes by better matching patients to treatments using…

PHA Will Host O2 Breathe Hearts PHor Hope Gala in Chicago

The country’s leading source of pulmonary hypertension patient and research support, the Pulmonary Hypertension Association, is hosting the first O2 Breathe Hearts PHor Hope Gala this month. The benefit will be spearheaded by the association’s Midwest Chapter to raise funds and awareness for this rare, life-altering, and…

Researchers Show How Microvasculature is Involved in CTEPH Pathogenesis

Patients with chronic thromboembolic pulmonary hypertension (CTEPH) who respond differently to treatment with pulmonary endarterectomy (PEA) may have differences in microvascular structure. When a team of researchers from Paris-South University and Centre Chirugical Marie Lannelongue investigated CTEPH pathogenesis in humans, they applied their findings related to microvasculature changes…

Physical Exam Unreliable in Predicting Pulmonary Hypertension

While the majority of individuals suspected of having pulmonary hypertension would prefer to receive a physical examination to confirm diagnosis, invasive right heart catheterization may still offer the most reliable indication of diagnosis. “Utility of the Physical Examination in Detecting Pulmonary Hypertension: A Mixed Methods…

Novel miRNAs and Molecule Inhibitors to Treat PAH

Naturally occurring microRNA molecules (miRNA) hold the potential to be a new treatment for pulmonary artery disease. A group at Sookmyung University and Yale University led by Professor Kim Jong-min investigated the causes of pulmonary arterial hypertension and discovered new molecular mechanism contributing to the disease. “Our research is…


A Conversation With Rare Disease Advocates