News

ISHLT Foundation Will Fund PH, Transplant Research Efforts

The International Society for Heart and Lung Transplantation (ISHLT) has launched the ISHLT Foundation, a new organization that will serve as ISHLT’s charitable arm to fund research grants and awards to improve patient care for advanced heart and lung diseases, including pulmonary hypertension (PH). In PH, high…

Mental Health Disorders Impair Quality of Life for CTEPH Patients

Nearly a third of individuals with chronic thromboembolic pulmonary hypertension (CTEPH) live with mental health disorders that impair their overall quality of life, a study in Germany has found. The significant impact of panic disorder, major depression, and other mental disorders on life quality suggests that adequate screening tools…

Oxygen Uptake in Exercise Test Predicts PH-LHD Outcomes: Study

Maximum oxygen uptake measured during cardiopulmonary exercise testing (CPET) independently predicted long-term survival outcomes in people with pulmonary hypertension caused by left heart disease (PH-LHD), a study reported. Further studies with a larger number of these patients are needed to confirm the findings, the researchers noted. The study, “…

Europe Awaits Proposed New Framework for Sharing Health Data

The European Commission is expected to propose a new governing framework for health data next month, called the European Health Data Space (EHDS), with the aim of connecting national health systems to facilitate secure and efficient transfer of data across systems in different European nations. The move is expected to…

CBD Therapy Lowers Arterial Blood Pressure in PH-mimicking Conditions

Treatment with DehydraTECH-CBD, Lexaria Bioscience’s investigational cannabis-derived treatment for pulmonary hypertension (PH), led to reduced pulmonary artery pressure in healthy volunteers who were exposed to low oxygen levels — especially among male participants — in conditions that mimicked PH. This was according to data from the now-completed HYPER-H21-3…

Combining Endpoints May Better Predict PAH Survival Outcomes

Combining measures of symptom severity, physical function, and heart health can help predict survival outcomes in pulmonary arterial hypertension (PAH), according to a new study. The study, “Prognostic value of improvement endpoints in pulmonary arterial hypertension trials: A COMPERA analysis,” was published in The Journal of Heart and…

Vascular Progenitor Cells’ Receptor Protein May Be New PAH Target

A receptor protein at the surface of lung vascular progenitor cells regulates the cells’ growth and maturation into smooth muscle cells, contributing to the vascular remodeling that characterizes pulmonary arterial hypertension (PAH), a study shows. Suppressing this protein — called platelet-derived growth factor receptor alpha (PDGFR-alpha) — prevents these progenitor…