News

Opsumit Shows Promise for Portopulmonary Hypertension in Phase 4 Trial

Treatment for 12 weeks with Actelion Pharmaceuticals’ Opsumit (macitentan) significantly improved blood vessels’ resistance in patients with portopulmonary hypertension without causing further damage to the liver, data from the PORTICO Phase 4 trial show. The study, “Macitentan for the treatment of portopulmonary hypertension (PORTICO): a multicentre, randomised, double-blind,…

AIT Therapeutics Secures $8M to Further its Nitric Oxide Delivery System for Respiratory Conditions

AIT Therapeutics has obtained a funding agreement that will raise $8 million through private investment in public equity (PIPE) financing to further development of its nitric oxide-based treatments for persistent pulmonary hypertension of the newborn, bronchiolitis, and nontuberculous mycobacteria. Nitric oxide (NO) is a strong vasodilator that opens blood vessels, and is…

Revatio Reduces Symptoms of PPHTN, Allowing Safe Liver Transplant, Case Report Shows

Treatment with Revatio (sildenafil) successfully reduced symptoms of portopulmonary hypertension (PPHTN), allowing patients to undergo liver transplant safely, a case report study shows. The case report study, “Sildenafil Monotherapy to Treat Portopulmonary Hypertension Before Liver Transplant,” was published in the journal Transplantation Proceedings. Pulmonary hypertension (PH)…