News

Specific Blood Flow Pattern in Patients with PH and Aortic Stenosis Linked to Poorer Outcomes, Study Reports

Patients with pulmonary hypertension (PH) and severe aortic stenosis (AS), who have a specific, less frequent blood flow pattern, have worse cardiac function and increased mortality, according to a study. The study, “Haemodynamic mechanisms and long‐term prognostic impact of pulmonary hypertension in patients with severe aortic stenosis undergoing valve…

Ventavis Shows Limited Ability to Improve Long-term Survival Rates in PAH Patients, Real-World Data Suggests

Treatment with inhaled Ventavis (iloprost) has limited effectiveness in improving the survival rate of patients with pulmonary arterial hypertension (PAH), despite the clinical improvements it induces, real-world data suggests. These findings resulted from an analysis of data collected in the observational Spanish REHAP registry. They were recently reported in…

PH-Targeted Therapies Show Modest-at-Best Benefit in PH Due to Left Heart Disease, Review Study Reports

A large review of clinical trials evaluating whether pulmonary hypertension (PH)-targeted therapies can improve exercise capacity in patients with pulmonary hypertension due to left heart disease (PH-LHD) found varying effectiveness and modest benefit. The findings were reported in the study “Pulmonary hypertension-targeted therapies in heart failure: A systematic…

Bellerophon’s Clinical Trials for INOpulse PH Therapies Moving Forward

Bellerophon Therapeutics has announced positive data from its Phase 3 clinical trial investigating INOpulse in patients with pulmonary arterial hypertension (PAH), as well as the enrollment of the first group of patients in its Phase 2b study testing INOpulse in patients with pulmonary hypertension associated with interstitial lung…