Posts by: Jose Marques Lopes, PhD

News, PH News

Pulmonary hypertension (PH) associated with bronchopulmonary dysplasia (BPD) resolves over time in nearly two-thirds of premature babies, a study shows. However, the findings also revealed that being male, steroid ... Read more

January 16, 2019January 16, 2019

Tracleer May Be More Cost-effective Than Some Other PAH Therapies, Review Study Reports

News, PAH News

Treatment of pulmonary arterial hypertension (PAH) with Tracleer (bosentan) may be more cost-effective than epoprostenol medications or palliative care, but less than Revatio (sildenafil) and other endothelin receptor blockers, ... Read more

January 10, 2019January 21, 2019

INOpulse Device Improves Physical Activity in PH-ILD Patients, Phase 2b Trial Shows

News

Treatment with INOpulse for eight weeks is safe and provides clinically meaningful improvements in physical activity in patients with pulmonary hypertension associated with interstitial lung disease (PH-ILD), according to ... Read more

January 3, 2019January 11, 2019

Obstructive Sleep Apnea Affects Cardiac Function of CTEPH Patients

CTEPH News, News

Worse measures of blood flow, arterial oxygenation, and cardiac function may underlie the poor clinical condition of chronic thromboembolic pulmonary hypertension (CTEPH) patients who also have obstructive sleep apnea ... Read more

December 19, 2018January 8, 2019

Anxiety and Depression in PAH Patients Could Be Eased with Psychosocial Therapies, Review Study Suggests

News, PAH News

Non-pharmacological approaches such as relaxation training, slow breathing, and cognitive behavioral therapy could help lessen anxiety and depression in patients with pulmonary arterial hypertension (PAH), according to a review ... Read more

November 29, 2018December 5, 2018

Specific Bone Marrow Cells Drive PAH Development, Blocking Serotonin Receptors a Potential Treatment, Study Suggests

News, PAH News, PH News

A subset of bone marrow cells known as proangiogenic cells (PACs) may drive the development of pulmonary arterial hypertension (PAH), according to a study that also showed that blocking ... Read more

November 21, 2018November 28, 2018

Arena Pharmaceuticals, United Therapeutics Reach Global Licensing Agreement for Ralinepag

News, PAH News

Arena Pharmaceuticals and United Therapeutics have reached a global licensing agreement for the pulmonary arterial hypertension (PAH) therapy candidate ralinepag. Ralinepag (APD811) is a next-generation, selective prostacyclin receptor agonist designed for oral ... Read more

November 1, 2018November 8, 2018

Specific Blood Flow Pattern in Patients with PH and Aortic Stenosis Linked to Poorer Outcomes, Study Reports

News

Patients with pulmonary hypertension (PH) and severe aortic stenosis (AS), who have a specific, less frequent blood flow pattern, have worse cardiac function and increased mortality, according to a study. The study, “Haemodynamic ... Read more

August 30, 2018September 3, 2018

Investigational Extended-Release Ralinepag for PAH Treatment Shows Favorable Results in Phase 1 Trials

News, PAH News

Extended-release tablets of ralinepag, Arena Pharmaceuticals’ treatment candidate for pulmonary arterial hypertension (PAH), show a superior pharmacokinetic profile over both immediate-release ralinepeg capsules and approved immediate-release medication Uptravi (selexipag), according ... Read more

August 13, 2018August 17, 2018

BET Proteins Could Be Therapeutic Target for COPD Patients with PH, Rat Study Suggests

News

Inhibition of proteins that regulate gene expression — called BET — were found to ease pulmonary hypertension (PH) in a rat model of chronic obstructive pulmonary disease (COPD), a study reports. ... Read more

Posts by: Jose Marques Lopes, PhD

Jose Marques Lopes, PhD

PH Linked to Bronchopulmonary Dysplasia Resolves Over Time in Many Preemies, Study Reports

Tracleer May Be More Cost-effective Than Some Other PAH Therapies, Review Study Reports

INOpulse Device Improves Physical Activity in PH-ILD Patients, Phase 2b Trial Shows

Obstructive Sleep Apnea Affects Cardiac Function of CTEPH Patients

Anxiety and Depression in PAH Patients Could Be Eased with Psychosocial Therapies, Review Study Suggests

Specific Bone Marrow Cells Drive PAH Development, Blocking Serotonin Receptors a Potential Treatment, Study Suggests

Arena Pharmaceuticals, United Therapeutics Reach Global Licensing Agreement for Ralinepag

Specific Blood Flow Pattern in Patients with PH and Aortic Stenosis Linked to Poorer Outcomes, Study Reports

Investigational Extended-Release Ralinepag for PAH Treatment Shows Favorable Results in Phase 1 Trials

BET Proteins Could Be Therapeutic Target for COPD Patients with PH, Rat Study Suggests

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