Posts by: Jose Marques Lopes, PhD

News

Inhibition of proteins that regulate gene expression — called BET — were found to ease pulmonary hypertension (PH) in a rat model of chronic obstructive pulmonary disease (COPD), a study reports. ... Read more

August 9, 2018August 13, 2018

Anti-cancer Therapy Sorafenib Reverses PAH in Rat Model, Study Reports

News, PAH News

Research & DevelopmentTreatment with the approved anti-cancer medication sorafenib reversed pulmonary arterial hypertension (PAH) and cardiopulmonary remodeling (CPR) in a rat model, according to a new study. The findings ... Read more

August 3, 2018August 8, 2018

Heart Arrhythmias Decrease Survival in PAH and CTEPH Patients, Study Suggests

CTEPH News, News, PAH News

Estimated survival in patients with either pulmonary arterial hypertension (PAH) or chronic thromboembolic pulmonary hypertension (CTEPH) is worse if they also have atrial arrhythmias, according to a new U.S. study. ... Read more

July 27, 2018July 27, 2018

SOX17 Gene May Contribute to PAH with Congenital Heart Disease, Study Suggests

PAH News

SOX17 may be a risk gene that contributes to pulmonary arterial hypertension (PAH) associated with congenital heart disease (CHD), as well as to idiopathic and/or familial PAH, according to ... Read more

July 16, 2018July 18, 2018

Oxidative Stress Enzyme May Be Central to PH Developing in COPD Patients, Study Reports

News, PH News

An enzyme called NOX4 appears to have a crucial role in the blood vessel remodeling that can lead to pulmonary hypertension (PH) in patients with chronic obstructive pulmonary disease (COPD), ... Read more

July 2, 2018July 4, 2018

Intravenous Iron Safe for Treating Low Oxygen Levels Related to PH, Study Suggests

News

Infusions of large doses of intravenous iron may be a safe treatment approach for patients with low oxygen levels in their blood due to pulmonary hypertension (PH) and/or congenital heart disease (CHD), ... Read more

June 18, 2018June 22, 2018

Cancer Marker NEDD9 Could Be a Therapeutic Target for PAH, Study Suggests

News, PAH News

A cancer marker called NEDD9 is a critical mediator of pulmonary arterial hypertension (PAH) and could be a therapeutic target, according to new research. The study, “NEDD9 targets COL3A1 ... Read more

May 31, 2018May 31, 2018

#ATS2018 – CTEPH May Be a Genetic Disease, Study Suggests

CTEPH News, News

Chronic thromboembolic pulmonary hypertension (CTEPH) may be an inherited genetic disease, a new study suggests. The results were recently presented at the American Thoracic Society (ATS) 2018 annual conference May 18-23 in ... Read more

May 9, 2018May 9, 2018

Age, Certain Comorbidities Predict Outcomes in Idiopathic PAH Patients, Study Shows

News, PAH News

Age, ischemic heart disease, and kidney dysfunction are important predictors of outcomes in patients with idiopathic pulmonary arterial hypertension (IPAH), a Swedish study shows. The research, “Impact of age and ... Read more

May 2, 2018May 2, 2018

Activation of PPAR-gamma May Be Potential Strategy Against PAH, Other Disorders, Study Suggests

News

Activation of a molecule called PPAR-gamma may be a future strategy to prevent pulmonary arterial hypertension (PAH) and other cardiovascular/pulmonary diseases, a study suggests. Findings were reported in the study, ... Read more

Posts by: Jose Marques Lopes, PhD

Jose Marques Lopes, PhD

BET Proteins Could Be Therapeutic Target for COPD Patients with PH, Rat Study Suggests

Anti-cancer Therapy Sorafenib Reverses PAH in Rat Model, Study Reports

Heart Arrhythmias Decrease Survival in PAH and CTEPH Patients, Study Suggests

SOX17 Gene May Contribute to PAH with Congenital Heart Disease, Study Suggests

Oxidative Stress Enzyme May Be Central to PH Developing in COPD Patients, Study Reports

Intravenous Iron Safe for Treating Low Oxygen Levels Related to PH, Study Suggests

Cancer Marker NEDD9 Could Be a Therapeutic Target for PAH, Study Suggests

#ATS2018 – CTEPH May Be a Genetic Disease, Study Suggests

Age, Certain Comorbidities Predict Outcomes in Idiopathic PAH Patients, Study Shows

Activation of PPAR-gamma May Be Potential Strategy Against PAH, Other Disorders, Study Suggests

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