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Ventavis Shows Limited Ability to Improve Long-term Survival Rates in PAH Patients, Real-World Data Suggests

Treatment with inhaled Ventavis (iloprost) has limited effectiveness in improving the survival rate of patients with pulmonary arterial hypertension (PAH), despite the clinical improvements it induces, real-world data suggests. These findings resulted from an analysis of data collected in the observational Spanish REHAP registry. They were recently reported in…

Scientists Discover New Genes and Signaling Pathways Involved in Severe Lung Disease in Premature Infants

A set of new genes and signaling pathways linked to the development of severe lung disease in premature infants was found by researchers from Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago and collaborators. Their study, “Exome sequencing identifies gene variants and…

PH-Targeted Therapies Show Modest-at-Best Benefit in PH Due to Left Heart Disease, Review Study Reports

A large review of clinical trials evaluating whether pulmonary hypertension (PH)-targeted therapies can improve exercise capacity in patients with pulmonary hypertension due to left heart disease (PH-LHD) found varying effectiveness and modest benefit. The findings were reported in the study “Pulmonary hypertension-targeted therapies in heart failure: A systematic…