PAH Therapy for Patients Unresponsive to Medication

Although advances in pharmacotherapies for pulmonary arterial hypertension (PAH) have been realized, a percentage of PAH patients still do not respond well to medication.

Researchers believe that specific patient segments could benefit from other therapy options like atrial septostomy, a Potts shunt or pulmonary artery denervation.

The proposed therapies are considered invasive, since most of them rely on surgical procedures. However, the researchers say they may be the best option for therapeutic or palliative treatment of PAH patient who are unresponsive to conventional medication-based therapies, and may improve their quality of life and their lifespan if performed with few or no complications.