7 Curious Facts About Pulmonary Arterial Hypertension

Marta Ribeiro avatar

by Marta Ribeiro |

Share this article:

Share article via email

What do you know about pulmonary arterial hypertension? Are you an expert in PAH? Maybe you are simply curious because someone you love has the life-threatening lung condition.

Here are some interesting facts you should know about PAH (source: Active Beat website):


pah facts1

PAH affects men and women of all ages and races. Women between the ages of 20 and 50 years old make up the most cases.

Who is more at risk of developing pulmonary hypertension?

pah facts2

The first recorded diagnosis can be traced back to Germany in 1891. Unfortunately at the time there were few treatments and the patient succumbed to the disease.

How is pulmonary hypertension diagnosed? Find out more here.

pah facts3

Patients affected with PAH often go years without a formal diagnosis. This is often due to not recognizing milder symptoms that come and go with exercise or other physical exertion.

Do you know how pulmonary hypertension develops?

pah facts4

This progressive disease begins with mild symptoms such as shortness of breath, chest pain, and fainting typically brought on by exercise or strenuous physical activity. That’s why it’s easy to shrug off symptoms in the early stages of the condition.

Find out 8 pulmonary hypertension red flag symptoms you need to know.

pah facts5

Although many factors are thought to contribute to PAH, more than 15 percent of all patients have heritable pulmonary arterial hypertension caused by one of two things:

  • A family history of pulmonary arterial hypertension
  • An autosomal dominant genetic condition caused by mutations in the BMPR2 gene or TGFbeta pathway
  • Diet drug use —i.e., Fen Phen, Pondimin, Redux, and methamphetamines.

Find out more about familial or heritable pulmonary hypertension here.

pah facts6

Eventually, the symptoms of PAH become impossible to ignore. Medical treatment will be necessary to control the internal blood pressure of the pulmonary artery and protect the heart muscles from weakening — and eventually failing.

Read more about some treatment options available for pulmonary hypertension.

pah facts7

Although there is no known cure for PAH, medications such as blood thinners and dilation aids are often prescribed to help the patient live a normal life. Organ transplant of the lungs and heart is only recommended for severe conditions when other therapies have not worked.

Even though there’s no cure for PH, there are several treatment options. Here are 7 medications you should know about.


Pulmonary Hypertension News is strictly a news and information website about the disease. It does not provide medical advice, diagnosis or treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or another qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.