An investigational fixed-dose combination of macitentan and tadalafil in a single tablet (M/T STCT) led to improvements in blood flow and reductions in a biomarker of heart failure for people with pulmonary arterial hypertension (PAH) who were treatment naïve or previously received monotherapies, according to final…

Note: This story was updated Sept. 28, 2020, to clarify that Uptravi was being tested as part of an initial triple combination strategy with Opsumit and tadalafil for newly diagnosed patients. An initial triple combination strategy of the oral therapies Uptravi (selexipag), Opsumit (macitentan),…

An updated guideline with new recommendations for the treatment of patients with pulmonary arterial hypertension (PAH) was released by the American College of Chest Physicians (CHEST). The free guide, titled “Therapy for Pulmonary Arterial Hypertension in Adults 2018: Update of the CHEST Guideline and Expert Panel Report…

Revatio (sildenafil) in low doses is safe and can be of benefit to children with pulmonary hypertension (PH), particularly those with early lung disease, a study reports. With this work, the researchers weighed in on a controversy, coming down in favor of the treatment. Revatio is approved to treat adults with pulmonary…

Chloe Temtchine is a well-known personality in the pulmonary hypertension (PH) community and in her latest ChloesPHriend vlog she talks about some of the medications she takes. MORE: Chloe Temtchine explains five key elements for improving PH health Chloe explains that she is…

Pulmonary arterial hypertension (PAH) patients who fail to respond completely to Adcirca (tadalafil) or Viagra (sildenafil) benefit from Letairis (ambrisentan) as an add-on therapy, according to a study. The research, “Clinical and hemodynamic improvements after adding ambrisentan to background PDE5i therapy in patients with pulmonary arterial hypertension exhibiting a…