A professor of pediatric cardiology at Stanford University School of Medicine will receive the American Heart Association 2023 Research Achievement Award, in recognition of her work in pulmonary arterial hypertension (PAH). Marlene Rabinovitch, MD, will receive the award Nov. 12 during the Presidential Session of the Association’s Scientific…

Note: This story was updated Aug. 11, 2021, to clarify that the researchers are not affiliated with the Virginia Tech Carilion School of Medicine. Two new researchers at Virginia Tech will be focusing their studies on the mechanisms of heart and vascular diseases — including the role of RNA molecules…

Preclinical work supports the potential of  sotatercept to be a first-in-class disease-modifying therapy for pulmonary arterial hypertension (PAH) and to moving the investigational therapy into a Phase 2 trial in patients, Acceleron Pharma announced. Sotatercept is a  trap molecule for members of the transforming growth factor-beta (TGF-beta) superfamily. A growing body of evidence…

ProMetic Life Sciences recently presented positive preclinical data on its fibrosis-targeting lead candidate, PBI-4050, showing that the drug effectively reduces pulmonary hypertension and right ventricular hypertrophy. The company also presented positive effects of PBI-4050 on cardiovascular biomarkers in patients with metabolic syndrome and type 2 diabetes. The data…

Rats with induced pulmonary hypertension (PH) and all its symptoms that were then treated with a modified strain of Lactobacillus, a probiotic bacteria engineered to produce a specific oral peptide, showed a reversal in those symptoms: reduced blood pressure, reduced heart wall thickness, and improved heart contractility. The results were recently…

The American Heart Association’s (AHA) journal Circulation has announced plans for a new thematic series on the recent advances in diagnosing and treating Pulmonary Hypertension (PH), in which an expert research team will present progress made in the research field for the disease. The topics in the series include patient…

In a recent review published in Circulation, the official Journal of the American Heart Association, Jonathan and Stuart Rich examined the current status of the epidemiology, prognosis, and update of the clinical classification for PH. In the review, the authors mainly focus on the diagnostic approach of suspected Pulmonary Hypertension…