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Although advances in pharmacotherapies for pulmonary arterial hypertension (PAH) have been realized, a percentage of PAH patients still do not respond well to medication. Researchers believe that specific patient segments could benefit from other therapy options like atrial septostomy, a Potts shunt or pulmonary artery denervation. The proposed therapies are…

Medikidz, with the collaboration of the Imperial College Healthcare NHS Trust, has launched a comic book in a peer-reviewed series on pulmonary hypertension (PH) . “Medikidz Explain Pulmonary Arterial Hypertension” is expected to not only increase knowledge and understanding about the disease, but also to support adults who struggle to…

A new set of heart and lungs have brought renewed hope to Oswaldo Jimenez and, through the innovative approach taken by his transplant team at Lucile Packard Children’s Hospital Stanford in California, a fresh chance at life. The Salem, Oregon, teenager, diagnosed with pulmonary arterial hypertension (PAH) at age…

Researchers in Turkey evaluated the two drug therapy approaches commonly used to treat pulmonary arterial hypertension (PAH) and found no substantial difference between the two in the patients observed. The study, titled “Combination Therapy in Pulmonary Arterial Hypertension: Single Centre Long-term Experience“ appeared in May 2015 in the West…

Researchers from Japan described ways to predict the progression and severity of pulmonary hypertension (PH) in people with left heart disease. Their paper, a review of standard and emerging methods for assessing the lung disease, is titled “The Roles of Classic and Current Prognostic Factors in Pulmonary Hypertension Due…

A new study by Romanian and Belgian scientists sheds light on specific conditions associated with pulmonary hypertension (PH), and which of those conditions are associated with a better prognosis for survival. The report, titled “Is Right Ventricular Remodeling in Pulmonary Hypertension Dependent on Etiology? An Echocardiographic Study,”appeared in the…

A recent article suggests prostacyclin therapy, which is used for the treatment of pulmonary arterial hypertension (PAH), may also be useful for treating sarcoidosis-associated pulmonary hypertension (SAPH). PAH refers to high blood pressure of the lungs. The condition can occur as a result of several different diseases, including sarcoidosis; a disease…

Gilead Sciences announced that the U.S. Food and Drug Administration (FDA) has approved Letairis® (ambrisentan) with tadalafil for pulmonary arterial hypertension (PAH) to diminish disease progression risk and hospitalization and to improve the ability to exercise — a decision that directly follows recent study results indicating the…

A recent study from Japan has shown that dividing cells involved in causing idiopathic pulmonary arterial hypertension (IPAH) may be stopped with a new type of drug called a calcilytic. The research could led to new treatments for IPAH. The study, titled “Inhibition of Excessive Cell Proliferation…

An international group of scientists has comprehensively characterized the genetics of pulmonary arterial hypertension (PAH). This new information could ultimately help clinicians treat the disease based on individual traits and genetic makeup. This is the most complete set of genetic data that has been collected about the disease to date.

Bellerophon Therapeutics recently announced that INOpulse, a type of nitric oxide that helps blood vessels expand, is effective in treating Pulmonary Arterial Hypertension (PAH) based on middle-stage data from a Phase 2 trial. The US Food and Drug Administration (FDA) has issued a Special Protocol Assessment (SPA), which will help to…

Reata Pharmaceuticals has announced that it will present Phase 2 results from a trial of its investigational therapy bardoxolone methyl in treating pulmonary arterial hypertension (PAH). The study’s findings will be presented October 27, 2015 at the 2015 American College of Chest Physicians (CHEST) annual meeting in Montreal, Canada in a…